European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for …

HF Hammer, MR Fox, J Keller… - United European …, 2022 - Wiley Online Library
Introduction Measurement of breath hydrogen (H2) and methane (CH4) excretion after
ingestion of test‐carbohydrates is used for different diagnostic purposes. There is a lack of …

Small intestinal bacterial overgrowth—pathophysiology and its implications for definition and management

D Bushyhead, EMM Quigley - Gastroenterology, 2022 - Elsevier
The concept of small intestinal bacterial overgrowth (SIBO) arose in the context of
maldigestion and malabsorption among patients with obvious risk factors that permitted the …

The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance

NS Scrimshaw, EB Murray - The American journal of clinical nutrition, 1988 - Elsevier
Most humans, like other mammals, gradually lose the intestinal enzyme lactase after infancy
and with it the ability to digest lactose, the principle sugar in milk. At some point in prehistory …

Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial …

D Yu, F Cheeseman, S Vanner - Gut, 2011 - gut.bmj.com
Objectives Recent studies using the lactulose hydrogen breath test (LHBT) suggest most
patients with irritable bowel syndrome (IBS) have small intestinal bacterial overgrowth …

Methanogenic flora is associated with altered colonic transit but not stool characteristics in constipation without IBS

A Attaluri, M Jackson, J Valestin… - Official journal of the …, 2010 - journals.lww.com
OBJECTIVES: About 35% of humans have methane-producing gut flora. Methane-producing
irritable bowel syndrome (IBS) subjects are generally constipated. In animal models …

Absorption capacity of fructose in healthy adults. Comparison with sucrose and its constituent monosaccharides.

JJ Rumessen, E Gudmand-Høyer - Gut, 1986 - gut.bmj.com
The capacity to absorb fructose in 10 healthy adults was investigated by means of hydrogen
breath analysis. Fructose absorption was quantified with lactulose standards. Significant …

Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial

CS Yuan, JF Foss, M O'Connor, J Osinski, T Karrison… - Jama, 2000 - jamanetwork.com
ContextConstipation is the most common chronic adverse effect of opioid pain medications
in patients who require long-term opioid administration, such as patients with advanced …

The patterns of small bowel motility: physiology and implications in organic disease and functional disorders

HUSEBYE - Neurogastroenterology & Motility, 1999 - Wiley Online Library
The physiology and pathophysiology of small bowel motility are reviewed with particular
focus on the motility patterns and periods that are detected by intraluminal manometry …

Functional bowel disease: malabsorption and abdominal distress after ingestion of fructose, sorbitol, and fructose-sorbitol mixtures

JJ Rumessen, E Gudmand-Høyer - Gastroenterology, 1988 - Elsevier
Twenty-five patients with functional bowel disease were given fructose, sorbitol, fructose-
sorbitol mixtures, and sucrose. The occurrence of malabsorption was evaluated by means of …

Rectal instillation of butyrate provides a novel clinically relevant model of noninflammatory colonic hypersensitivity in rats

S Bourdu, M Dapoigny, E Chapuy, F Artigue… - Gastroenterology, 2005 - Elsevier
Background & Aims: The treatment of irritable bowel syndrome (IBS), characterized by
abdominal pain and bloating, is empirical and often poorly efficient. Research lacks suitable …