Alzheimer's disease (AD) is a debilitating, chronic neurodegenerative disease. Genetic
studies involving genome-wide association studies (GWAS) and meta-analysis have …

Alzheimer's disease (AD) is a debilitating neurological disorder, and currently, there is no
cure for it. Several pathologic alterations have been described in the brain of AD patients …

Microglia become progressively activated and seemingly dysfunctional with age, and
genetic studies have linked these cells to the pathogenesis of a growing number of …

Presenilin mutations that alter γ-secretase activity cause familial Alzheimer's disease (AD),
whereas ApoE4, an apolipoprotein for cholesterol transport, predisposes to sporadic AD …

Background The role of physical exercise in the prevention of Alzheimer's disease (AD) has
been widely studied. Microglia play an important role in AD. Triggering receptor expressed …

Increasing life expectancy has led to an aging population, which has consequently
increased the prevalence of dementia. Alzheimer's disease (AD), the most common form of …

Although amyloid-β (Aβ) peptide accumulation is considered as a key early event in the
pathogenesis of Alzheimer's disease (AD), the precise pathophysiology of this deadly illness …

Genetic Alzheimer's disease (AD) risk factors associate with reduced defensive amyloid β
plaque-associated microglia (AβAM), but the contribution of modifiable AD risk factors to …

Sepsis-associated encephalopathy (SAE) is the cognitive impairment resulting from sepsis
and is associated with increased morbidity and mortality. Hydrogen has emerged as a …

Microglia are resident Mϕs of the CNS that play pleiotropic functions in brain development
and homeostasis. Impaired microglial functions are thought to be involved in the onset and …