A review on free radicals and antioxidants

H Alkadi - Infectious Disorders-Drug Targets (Formerly Current …, 2020 - ingentaconnect.com
Free radicals are generated in our body by several systems. A balance among free radicals
and antioxidants is an important matter for appropriate physiological function. If free radicals …

The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases

KC Chang, PF Liu, CH Chang, YC Lin, YJ Chen… - Cell & bioscience, 2022 - Springer
Oxidative stress is mainly caused by intracellular reactive oxygen species (ROS) production,
which is highly associated with normal physiological homeostasis and the pathogenesis of …

PLA2G6 guards placental trophoblasts against ferroptotic injury

O Beharier, VA Tyurin, JP Goff… - Proceedings of the …, 2020 - National Acad Sciences
The recently identified ferroptotic cell death is characterized by excessive accumulation of
hydroperoxy-arachidonoyl (C20: 4)-or adrenoyl (C22: 4)-phosphatidylethanolamine (Hp …

Molecular mechanisms of zinc as a pro-antioxidant mediator: clinical therapeutic implications

AS Prasad, B Bao - Antioxidants, 2019 - mdpi.com
The essentiality of zinc as a trace mineral in human health has been recognized for over five
decades. Zinc deficiency, caused by diet, genetic defects, or diseases, can cause growth …

Retinal degeneration and Alzheimer's disease: an evolving link

A Ashok, N Singh, S Chaudhary… - International journal of …, 2020 - mdpi.com
Age-related macular degeneration (AMD) and glaucoma are degenerative conditions of the
retina and a significant cause of irreversible blindness in developed countries. Alzheimer's …

Biomarkers of inflammation and oxidative stress in ophthalmic disorders

A Ahmad, H Ahsan - Journal of Immunoassay and …, 2020 - Taylor & Francis
The review article focuses on free radicals and oxidative stress involved in ophthalmological
diseases such as retinopathy, cataract, glaucoma, etc. Oxidative stress is considered as a …

Oxidative stress in the anterior ocular diseases: diagnostic and treatment

A Dammak, C Pastrana, A Martin-Gil… - Biomedicines, 2023 - mdpi.com
The eye is a metabolically active structure, constantly exposed to solar radiations making its
structure vulnerable to the high burden of reactive oxygen species (ROS), presenting many …

Molecular characteristics and structure–activity relationships of food-derived bioactive peptides

FJ Yang, C Xu, MC Huang, Y Qian, XX Cai… - Journal of Integrative …, 2021 - Elsevier
Peptides are functional active fragments of proteins which can provide nutrients needed for
human growth and development, and they also have unique physiological activity …

Antioxidant defenses in the human eye: A focus on metallothioneins

A Álvarez-Barrios, L Álvarez, M García, E Artime… - Antioxidants, 2021 - mdpi.com
The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of
endogenous and exogenous origin. Oxidative stress affects all structures of the human eye …

Oxidative stress implication in retinal diseases—A review

M Nebbioso, F Franzone, A Lambiase, V Bonfiglio… - Antioxidants, 2022 - mdpi.com
Oxidative stress (OS) refers to an imbalance between free radicals (FRs), namely highly
reactive molecules normally generated in our body by several pathways, and intrinsic …