Paracrine mechanisms of mesenchymal stem cells in tissue repair
M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies
P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
[HTML][HTML] Challenges and strategies for improving the regenerative effects of mesenchymal stromal cell-based therapies
S Baldari, G Di Rocco, M Piccoli, M Pozzobon… - International journal of …, 2017 - mdpi.com
Cell-based therapies have the potential to revolutionize current treatments for diseases with
high prevalence and related economic and social burden. Unfortunately, clinical trials have …
high prevalence and related economic and social burden. Unfortunately, clinical trials have …
Paracrine mechanisms in adult stem cell signaling and therapy
Animal and preliminary human studies of adult cell therapy following acute myocardial
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …
[HTML][HTML] Clinical applications of mesenchymal stem cells
S Wang, X Qu, RC Zhao - Journal of hematology & oncology, 2012 - Springer
Mesenchymal stem cells (MSC) have generated a great amount of enthusiasm over the past
decade as a novel therapeutic paradigm for a variety of diseases. Currently, MSC based …
decade as a novel therapeutic paradigm for a variety of diseases. Currently, MSC based …
Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer
M Walraven, B Hinz - Matrix Biology, 2018 - Elsevier
Organ fibrosis is characterized by the accumulation of disorganized and stiff extracellular
matrix (ECM) and represents the final stage of several life-threatening diseases. The …
matrix (ECM) and represents the final stage of several life-threatening diseases. The …
Heme oxygenase-1 and carbon monoxide in the heart: the balancing act between danger signaling and pro-survival
LE Otterbein, R Foresti, R Motterlini - Circulation research, 2016 - Am Heart Assoc
Understanding the processes governing the ability of the heart to repair and regenerate after
injury is crucial for developing translational medical solutions. New avenues of exploration …
injury is crucial for developing translational medical solutions. New avenues of exploration …
Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements
J Doorn, G Moll, K Le Blanc… - … Engineering Part B …, 2012 - liebertpub.com
Among the various types of cell-to-cell signaling, paracrine signaling comprises those
signals that are transmitted over short distances between different cell types. In the human …
signals that are transmitted over short distances between different cell types. In the human …
How to improve the survival of transplanted mesenchymal stem cell in ischemic heart?
L Li, X Chen, WE Wang, C Zeng - Stem Cells International, 2016 - Wiley Online Library
Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac
repair. For decades, the preclinical researches on animal model and clinical trials have …
repair. For decades, the preclinical researches on animal model and clinical trials have …
[HTML][HTML] Clinical applications of mesenchymal stem cells
N Kim, SG Cho - The Korean journal of internal medicine, 2013 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with
multilineage potential to differentiate into cell types of mesodermal origin, such as …
multilineage potential to differentiate into cell types of mesodermal origin, such as …