Quinone-based fluorophores for imaging biological processes
GG Dias, A King, F De Moliner, M Vendrell… - Chemical Society …, 2018 - pubs.rsc.org
Quinones are privileged chemical structures playing crucial roles as redox and alkylating
agents in a wide range of processes in cells. The broad functional array of quinones has …
agents in a wide range of processes in cells. The broad functional array of quinones has …
Imidazoles and Oxazoles from Lapachones and Phenanthrene‐9, 10‐dione: A Journey through their Synthesis, Biological Studies, and Optical Applications
GG Dias, ERS Paz, MP Nunes… - The Chemical …, 2021 - Wiley Online Library
Diverse structural frameworks are found in natural compounds and are well known for their
chemical and biological properties; such compounds include the imidazoles and oxazoles …
chemical and biological properties; such compounds include the imidazoles and oxazoles …
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2
LH Santos, T Kronenberger, RG Almeida… - Journal of Chemical …, 2022 - ACS Publications
The worldwide COVID-19 pandemic caused by the coronavirus SARS-CoV-2 urgently
demands novel direct antiviral treatments. The main protease (Mpro) and papain-like …
demands novel direct antiviral treatments. The main protease (Mpro) and papain-like …
On the fine‐tuning of the excited‐state intramolecular proton transfer (ESIPT) process in 2‐(2′‐hydroxybenzofuran) benzazole (HBBX) dyes
E Heyer, K Benelhadj, S Budzák… - … A European Journal, 2017 - Wiley Online Library
Herein, a full investigation of the optical properties and first‐principles calculations of a large
series of original 2‐(2′‐hydroxybenzofuran) benzazole (HBBX) dyes is described. The …
series of original 2‐(2′‐hydroxybenzofuran) benzazole (HBBX) dyes is described. The …
Imidazole-based optical sensors as a platform for bisulfite sensing and BSA/HSA interaction study. An experimental and theoretical investigation
ERS Paz, VG Isoppo, FS dos Santos… - Journal of Molecular …, 2023 - Elsevier
The fluorescent lapachones were obtained from lapachol, a natural product extracted from
the heartwood of Tabebuia sp.(Tecoma). The extracted lapachol was oxidized and cyclized …
the heartwood of Tabebuia sp.(Tecoma). The extracted lapachol was oxidized and cyclized …
Rhodium (III)-Catalyzed C–H/N–H Alkyne Annulation of Nonsymmetric 2-Aryl (Benz) imidazole Derivatives: Photophysical and Mechanistic Insights
GG Dias, ERS Paz, JY Kadooca… - The Journal of …, 2020 - ACS Publications
Rhodium (III) catalysis enabled C–H/N–H alkyne annulation of nonsymmetric imidazole
derivatives. This study encompasses the synthesis of imidazoles from a naturally occurring …
derivatives. This study encompasses the synthesis of imidazoles from a naturally occurring …
From Live Cells to Caenorhabditis elegans: Selective Staining and Quantification of Lipid Structures Using a Fluorescent Hybrid Benzothiadiazole Derivative
AAR Mota, JR Correa, LP de Andrade… - ACS …, 2018 - ACS Publications
The current article describes the synthesis, characterization, and application of a designed
hybrid fluorescent BTD–coumarin (2, 1, 3-benzothiadiazole-coumarin) derivative (named …
hybrid fluorescent BTD–coumarin (2, 1, 3-benzothiadiazole-coumarin) derivative (named …
Fluorescent oxazoles from quinones for bioimaging applications
This work describes a synthetic strategy for the syntheses of four new fluorescent excited
state intramolecular proton transfer (ESIPT) prone oxazole derivatives synthesized from …
state intramolecular proton transfer (ESIPT) prone oxazole derivatives synthesized from …
Fluorescent peptoids as selective live cell imaging probes
STA Passos, JR Correa, SLM Soares… - The Journal of …, 2016 - ACS Publications
This paper describes the synthesis of fluorescent peptoids using the Ugi multicomponent
reaction (4CR). The four synthesized structures had their photophysical properties evaluated …
reaction (4CR). The four synthesized structures had their photophysical properties evaluated …
Natural product-inspired profluorophores for imaging NQO1 activity in tumour tissues
Herein we designed a collection of trimethyl-lock quinone profluorophores as activity-based
probes for imaging NAD (P) H: quinone oxidoreductase (NQO1) in cancer cells and tumour …
probes for imaging NAD (P) H: quinone oxidoreductase (NQO1) in cancer cells and tumour …