In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have
shown promising results in the diagnosis of cancer and several other diseases, making them …

Introduction Fibroblast activation protein-α (FAPα) is overexpressed on cancer-associated
fibroblasts in approximately 90% of epithelial neoplasms, representing an appealing target …

Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among
them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are associated with a poor …

Purpose The lack of effective molecular biomarkers to monitor idiopathic pulmonary fibrosis
(IPF) activity or treatment response remains an unmet clinical need. Herein, we determined …

Fibroblast-activation protein (FAP) is a serine protease classified in the dipeptidyl peptidase
4 (DPP4) family. FAP is predominantly expressed in activated fibroblasts such as the cancer …

Background In Crohn disease, differentiation between active intestinal inflammation and
fibrosis has implications for treatment, but current imaging modalities are not reliably …

Myocardial fibrosis is the heart's common healing response to injury. While initially seeking
to optimize the strength of diseased tissue, fibrosis can become maladaptive, producing stiff …

Despite revolutionizing the field of oncological imaging, Positron Emission Tomography
(PET) with [18F] Fluorodeoxyglucose (FDG) as its workhorse is limited by a lack of specificity …

Purpose Myocardial fibrosis (MF) is a factor of poor prognosis in systemic sclerosis (SSc).
Direct in-vivo visualization of fibroblast activation as early readout of MF has not been …

Fibroblast activation protein (FAP), overexpressed on cancer-associated fibroblasts (CAFs),
is a novel target for molecular imaging of various tumors. Recently, the development of …