Nano-sized magnetic particles are increasingly being used across a wide spectrum of
biomedical fields. Upon functionalization to enable specific binding, magnetic particles and …

Sample preparation is one of the most crucial processes in proteomics research. The results
of the experiment depend on the condition of the starting material. Therefore, the proper …

Recent studies have established distinctive serum polypeptide patterns through mass
spectrometry (MS) that reportedly correlate with clinically relevant outcomes. Wider …

Normalization is critically important for the proper interpretation of matrix-assisted laser
desorption/ionization (MALDI) imaging datasets. The effects of the commonly used …

There is a saying,“Eyes are the windows to the soul”. In much the same vein, blood, since it
flows through the entire body, can be considered the window to the physical condition of the …

Individualized medicine is the healthcare strategy that rebukes the idiomatic dogma of
'losing sight of the forest for the trees'. We are entering a new era of healthcare where it is no …

Serum is an ideal biological sample that contains an archive of information due to the
presence of a variety of proteins released by diseased tissue, and serum proteomics has …

In this article, we present an overview of the different strategies for sample preparation for
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …

Profiling and imaging biological specimens using MALDI mass spectrometry has significant
potential to contribute to our understanding and diagnosis of disease. The technique is …

A glycomic approach is developed to identify oligosaccharide markers for ovarian cancer by
rapidly profiling globally released oligosaccharides. Glycoproteins shed by cancer cells are …