Synthetic Toll-like receptor agonists for the development of powerful malaria vaccines: a patent review

A Kaur, D Kannan, SK Mehta, S Singh… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Currently, there is no efficient vaccine available against clinical malaria.
However, continuous efforts have been committed to develop powerful antimalarial vaccine …

Changes in the immune system in experimental acanthamoebiasis in immunocompetent and immunosuppressed hosts

N Łanocha-Arendarczyk, A Kolasa-Wołosiuk… - Parasites & vectors, 2018 - Springer
Background Acanthamoebiasis is most often found in patients with immune deficiency, with
infections facilitated by the intake of immunosuppressive drugs. The host immune response …

Efficacy of TLR7 agonistic imidazoquinoline as immunochemotherapeutic agent against P. Berghei ANKA infected rodent host

R Saroa, D Kaushik, U Bagai, S Kaur… - Bioorganic & Medicinal …, 2019 - Elsevier
Malaria is a serious disease and is one of the most alarming public health issues.
Plasmodium is being resistant to various antimalarials including Chloroquine (CQ) which …

Merozoite-Protein Loaded Liposomes Protect against Challenge in Two Murine Models of Plasmodium Infection

WL Fotoran, MC Colhone, P Ciancaglini… - ACS Biomaterials …, 2016 - ACS Publications
Liposomes loaded with GPI-anchored proteins induce a strong and effective response
against protozoan pathogens when immunized in mice. On the basis of results using …

Sodium arsenite exposure impairs B cell proliferation and enhances vascular inflammation in Plasmodium berghei mouse model

S Suntararuks, L Worasuttayangkurn… - Environmental …, 2019 - Elsevier
Arsenic exposure has been linked to an impaired immune response and inflammation. Our
study investigated the effects of sodium arsenite on host immune response and vascular …

[图书][B] Drug Development for Malaria: Novel Approaches for Prevention and Treatment

P Kendrekar - 2022 - books.google.com
Drug Development for Malaria Provides readers with first-hand advice for the development
of novel antimalarial drugs This book provides a systematic overview of antimalarial drug …

Pure TLR 7 Agonistic BBIQ is a Potential Adjuvant Against Plasmodium berghei …

R Saroa, D Kaushik, A Rakha, U Bagai… - … for Malaria: Novel …, 2022 - Wiley Online Library
The present study examined the effect of pure TLR7 agonistic 1‐benzyl‐2‐butyl‐1 H‐
imidazo [4, 5‐c] quinolin‐4‐amine (BBIQ) as an adjuvant along with the blood stage fraction …

Role of White Blood Cells in Immunopathogenesis of Cerebral Malaria

R Saroa, U Bagai - Infectious Diseases and Your Health, 2018 - Springer
Cerebral malaria (CM) is a fatal complication caused by Plasmodium falciparum in humans
claiming two million lives annually. The pathogenesis of this disease yet remains partially …

Immunophenotyping of blood mononuclear cells from P. berghei (NK-65) infected and immunized BALB/c mice

V Kumar, A Rakha, R Saroa, U Bagai - Journal of Parasitic Diseases, 2017 - Springer
The present study demonstrates the alterations in the frequencies of helper, cytotoxic and
suppressor T cells in blood of P. berghei infected and TPA immunized rodent host towards …

[引用][C] Research and Reviews: Journal of Zoological Sciences

B Seliya