S100 is a multigenic family of non-ubiquitous Ca2+-modulated proteins of the EF-hand type
expressed in vertebrates exclusively and implicated in intracellular and extracellular …

α‐Enolase is a key glycolytic enzyme in the cytoplasm of prokaryotic and eukaryotic cells
and is considered a multifunctional protein. α‐enolase is expressed on the surface of …

S100, a multigenic family of non‐ubiquitous Ca2+‐modulated proteins of the EF‐hand type
expressed in vertebrates exclusively, has been implicated in intracellular and extracellular …

Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …

Investigators have been studying the expression and activity of proteases in the final steps of
tumor progression, invasion and metastasis, for the past 30 years. Recent studies, however …

A multigenic family of Ca2+-binding proteins of the EF-hand type known as S100 comprises
19 members that are differentially expressed in a large number of cell types. Members of this …

The S100 proteins comprise at least 25 members, forming the largest group of EF-hand
signalling proteins in humans. Although the proteins are expressed in many tissues, each …

Annexin A2 is a calcium-dependent, phospholipid-binding protein found on various cell
types. It is up-regulated in various tumor types and plays multiple roles in regulating cellular …

Many advanced tumors overexpress and secrete the S100A4 protein that is known to
promote angiogenesis and metastasis development. The mechanisms of this effect and the …

Annexin A2 (ANXA2) orchestrates multiple biologic processes and clinical associations,
especially in cancer progression. The structure of ANXA2 affects its cellular localization and …