Cardiovascular imaging has become an indispensable tool for patient diagnosis and follow
up. Probably the wide clinical applications of imaging are due to the possibility of a detailed …

Pulmonary arterial hypertension (PAH), the most serious chronic disorder of the pulmonary
circulation, is characterized by pulmonary vasoconstriction and remodeling, resulting in …

Autophagy plays an important role in the maintenance of normal heart function. However,
the role of autophagy in the inulin resistant and diabetic heart is not well understood …

Background: The failing right ventricle (RV) does not respond like the left ventricle (LV) to
guideline-directed medical therapy of heart failure, perhaps due to interventricular …

Pulmonary artery banding (PAB) causes right ventricular (RV) dysfunction, biventricular
fibrosis, and apoptosis, which are attenuated by endothelin-1 receptor blockade (ERB). Little …

Background Right ventricle failure (RVF) is associated with serious cardiac and pulmonary
diseases that contribute significantly to the morbidity and mortality of patients. Currently, the …

Right ventricular failure (RVF) is a lethal condition in diverse pathologies. Pressure overload
is the most common etiology of RVF, but our understanding of the tissue structure …

Aims: Autophagy is a catabolic process required for the maintenance of cardiac health.
Insulin and insulin-like growth factor 1 (IGF-1) are potent inhibitors of autophagy and as …

Background Right ventricular (RV) failure (RVF) is a vexing problem facing patients with
various disease processes and carries a high mortality. RVF is a poorly understood …

OBJECTIVES Right ventricular (RV) failure from increased pressure loading is a frequent
consequence of acquired and congenital heart diseases. However, the mechanisms …