A conserved molecular machinery centered on the Cdc42 GTPase regulates cell polarity in
diverse organisms. Here we review findings from budding and fission yeasts that reveal both …

Active Cdc42 is essential for the establishment of polarized growth. This GTPase is
negatively regulated by the GTPase-activating proteins (GAPs), which are important for the …

During anaphase B, molecular motors slide interpolar microtubules to elongate the mitotic
spindle, contributing to the separation of chromosomes. However, sliding of antiparallel …

Cells exist in an astonishing range of volumes across and within species. However, our
understanding of cell size control remains limited, owing in large part to the challenges …

Cell polarity and morphogenesis are regulated by the small GTPase Cdc42. Even though
major advances have been done in the field during the last years, the molecular details …

We are pleased to announce that the joint winners of the 2022 JCS Prize are Kathleen
Scheffler, Federica Giannini and Tom Lemonnier for their paper entitled 'The prophase …

The mitotic spindle is a bipolar structure that segregates the chromosomes during mitosis.
The main components of the spindle are microtubules: polymers that can grow and shrink at …

細胞内の様々な部位に局在する AAA (ATPases associated with diverse cellular activities)
ATPase は, 主にタンパク質複合体の解離やタンパク質の分解において機能する 1). 黄麹菌 …