Life depends as much on the flow of information as on the flow of energy. Here we review
the many efforts to make this intuition precise. Starting with the building blocks of information …

As information flows through the brain, neuronal firing progresses from encoding the world
as sensed by the animal to driving the motor output of subsequent behavior. One of the more …

The computation represented by a sensory neuron's response to stimuli is constructed from
an array of physiological processes both belonging to that neuron and inherited from its …

A key problem in computational neuroscience is to find simple, tractable models that are
nevertheless flexible enough to capture the response properties of real neurons. Here we …

The nervous system extracts information from its environment and distributes and processes
that information to inform and drive behaviour. In this task, the nervous system faces a type …

The ability to evaluate variability in the environment is vital for making optimal behavioral
decisions. Here we show that Caenorhabditis elegans evaluates variability in its food …

Rich, dynamic, and dense sensory stimuli are encoded within the nervous system by the
time-varying activity of many individual neurons. A fundamental approach to understanding …

Natural stimuli elicit robust responses of neurons throughout sensory pathways, and
therefore their use provides unique opportunities for understanding sensory coding. This …

High-level neurons processing complex, behaviorally relevant signals are sensitive to
conjunctions of features. Characterizing the receptive fields of such neurons is difficult with …

When visual contrast changes, retinal ganglion cells adapt by adjusting their sensitivity as
well as their temporal filtering characteristics. The latter has classically been described by …