Pathophysiology of traumatic brain injury

KJ Dixon - Physical Medicine and Rehabilitation Clinics, 2017 - pmr.theclinics.com
Traumatic brain injury (TBI) may have many different causes, including a blow to the head,
penetration of the skull, fast acceleration or deceleration of the head, or exposure to a blast …

Behavioral deficits in animal models of blast traumatic brain injury

A Aravind, AR Ravula, N Chandra, BJ Pfister - Frontiers in neurology, 2020 - frontiersin.org
Blast exposure has been identified to be the most common cause for traumatic brain injury
(TBI) in soldiers. Over the years, rodent models to mimic blast exposures and the behavioral …

Primary blast brain injury mechanisms: current knowledge, limitations, and future directions

E Fievisohn, Z Bailey, A Guettler… - Journal of …, 2018 - asmedigitalcollection.asme.org
Mild blast traumatic brain injury (bTBI) accounts for the majority of brain injury in United
States service members and other military personnel worldwide. The mechanisms of primary …

Loss of consciousness and righting reflex following traumatic brain injury: predictors of post-injury symptom development (a narrative review)

R Berman, H Spencer, M Boese, S Kim, K Radford… - Brain sciences, 2023 - mdpi.com
Identifying predictors for individuals vulnerable to the adverse effects of traumatic brain
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …

Roadmap for advancing pre-clinical science in traumatic brain injury

DH Smith, PM Kochanek, S Rosi, R Meyer… - Journal of …, 2021 - liebertpub.com
Pre-clinical models of disease have long played important roles in the advancement of new
treatments. However, in traumatic brain injury (TBI), despite the availability of numerous …

Linking blast physics to biological outcomes in mild traumatic brain injury: Narrative review and preliminary report of an open-field blast model

H Song, J Cui, A Simonyi, CE Johnson… - Behavioural brain …, 2018 - Elsevier
Blast exposures are associated with traumatic brain injury (TBI) and blast-induced TBIs are
common injuries affecting military personnel. Department of Defense and Veterans …

Effects of mild blast traumatic brain injury on cognitive-and addiction-related behaviors

MJ Muelbl, ML Slaker, AS Shah, NN Nawarawong… - Scientific reports, 2018 - nature.com
Traumatic brain injury (TBI) commonly results in cognitive and psychiatric problems.
Cognitive impairments occur in approximately 30% of patients suffering from mild TBI …

A neuroglia-based interpretation of glaucomatous neuroretinal rim thinning in the optic nerve head

EJ Lee, JC Han, C Kee - Progress in Retinal and Eye Research, 2020 - Elsevier
Neuroretinal rim thinning (NRR) is a characteristic glaucomatous optic disc change.
However, the precise mechanism of the rim thinning has not been completely elucidated …

Chronic post-traumatic stress disorder-related traits in a rat model of low-level blast exposure

G Perez-Garcia, MAG Sosa, R De Gasperi… - Behavioural brain …, 2018 - Elsevier
The postconcussion syndrome following mild traumatic brain injuries (mTBI) has been
regarded as a mostly benign syndrome that typically resolves in the immediate months …

Transient disruption of mouse home cage activities and assessment of orexin immunoreactivity following concussive-or blast-induced brain injury

PA Vu, LB Tucker, J Liu, EH McNamara, T Tran, AH Fu… - Brain research, 2018 - Elsevier
The employment of explosive weaponry in modern warfare exposes populations to shock
wave-induced and impact-related brain injuries. Among the most common clinical …