Environmental parameters associated with incidence and transmission of pathogenic Vibrio spp.

KD Brumfield, M Usmani, KM Chen… - Environmental …, 2021 - Wiley Online Library
Vibrio spp. thrive in warm water and moderate salinity, and they are associated with aquatic
invertebrates, notably crustaceans and zooplankton. At least 12 Vibrio spp. are known to …

The Interface of Vibrio cholerae and the Gut Microbiome

JY Cho, R Liu, JC Macbeth, A Hsiao - Gut Microbes, 2021 - Taylor & Francis
The bacterium Vibrio cholerae is the etiologic agent of the severe human diarrheal disease
cholera. The gut microbiome, or the native community of microorganisms found in the …

A commensal-encoded genotoxin drives restriction of Vibrio cholerae colonization and host gut microbiome remodeling

J Chen, H Byun, R Liu, IJ Jung, Q Pu… - Proceedings of the …, 2022 - National Acad Sciences
Members of complex microbial communities that reside in environments such as the
mammalian gut have evolved mechanisms of interspecies competition, which may be …

Gut microbiome signatures and host colonization with multidrug-resistant bacteria

NS Isles, A Mu, JC Kwong, BP Howden… - Trends in Microbiology, 2022 - cell.com
The human gut is host to a diverse range of microorganisms that offer protection against
colonization by multidrug-resistant bacteria. Antibiotic use, medications, health conditions …

[HTML][HTML] Therapeutic approach targeting gut microbiome in gastrointestinal infectious diseases

Z Han, Y Min, K Pang, D Wu - International Journal of Molecular Sciences, 2023 - mdpi.com
While emerging evidence highlights the significance of gut microbiome in gastrointestinal
infectious diseases, treatments like Fecal Microbiota Transplantation (FMT) and probiotics …

Immune evasion and persistence in enteric bacterial pathogens

M J. Worley - Gut Microbes, 2023 - Taylor & Francis
The major function of the mammalian immune system is to prevent and control infections
caused by enteropathogens that collectively have altered human destiny. In fact, as the …

Animal models for dissecting Vibrio cholerae intestinal pathogenesis and immunity

B Sit, B Fakoya, MK Waldor - Current opinion in microbiology, 2022 - Elsevier
Highlights•Mammalian, non-mammalian, and invertebrate species are currently used to
model Vibrio cholerae pathogenicity.•Models vary considerably in their recapitulation of V …

[HTML][HTML] Predicting Vibrio cholerae infection and symptomatic disease: a systems serology study

KE Wiens, AS Iyer, TR Bhuiyan, LL Lu… - The Lancet …, 2023 - thelancet.com
Background Vibriocidal antibodies are currently the best characterised correlate of
protection against cholera and are used to gauge immunogenicity in vaccine trials. Although …

Mucosal and systemic immune responses to Vibrio cholerae infection and oral cholera vaccines (OCVs) in humans: a systematic review

A Naidu, S Lulu S - Expert review of clinical immunology, 2022 - Taylor & Francis
Introduction Cholera is an enteric disease caused by Vibrio cholerae, a water-borne
pathogen, and characterized by severe diarrhea. Vaccines have been recommended for use …

Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement

K Barrasso, D Chac, MD Debela, C Geigel… - Elife, 2022 - elifesciences.org
Recent studies indicate that the human intestinal microbiota could impact the outcome of
infection by Vibrio cholerae, the etiological agent of the diarrheal disease cholera. A …