[HTML][HTML] Tuberculosis and lung damage: from epidemiology to pathophysiology
S Ravimohan, H Kornfeld, D Weissman… - European respiratory …, 2018 - Eur Respiratory Soc
A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …
Innate immunity in tuberculosis: host defense vs pathogen evasion
CH Liu, H Liu, B Ge - Cellular & molecular immunology, 2017 - nature.com
The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …
[HTML][HTML] Host evasion and exploitation schemes of Mycobacterium tuberculosis
Tuberculosis, an ancient disease of mankind, remains one of the major infectious causes of
human death. We examine newly discovered facets of tuberculosis pathogenesis and …
human death. We examine newly discovered facets of tuberculosis pathogenesis and …
Revisiting the role of the granuloma in tuberculosis
L Ramakrishnan - Nature Reviews Immunology, 2012 - nature.com
The granuloma, which is a compact aggregate of immune cells, is the hallmark structure of
tuberculosis. It is historically regarded as a host-protective structure that'walls off'the infecting …
tuberculosis. It is historically regarded as a host-protective structure that'walls off'the infecting …
Macrophages in tuberculosis: friend or foe
E Guirado, LS Schlesinger, G Kaplan - Seminars in immunopathology, 2013 - Springer
Tuberculosis (TB) remains one of the greatest threats to human health. The causative
bacterium, Mycobacterium tuberculosis (Mtb), is acquired by the respiratory route. It is …
bacterium, Mycobacterium tuberculosis (Mtb), is acquired by the respiratory route. It is …
Cavitary tuberculosis: the gateway of disease transmission
ME Urbanowski, AA Ordonez… - The Lancet Infectious …, 2020 - thelancet.com
Tuberculosis continues to be a major threat to global health. Cavitation is a dangerous
consequence of pulmonary tuberculosis associated with poor outcomes, treatment relapse …
consequence of pulmonary tuberculosis associated with poor outcomes, treatment relapse …
Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium
Granulomas, organized aggregates of immune cells, are a hallmark of tuberculosis and
have traditionally been thought to restrict mycobacterial growth. However, analysis of …
have traditionally been thought to restrict mycobacterial growth. However, analysis of …
Drylands in the earth system
DS Schimel - Science, 2010 - science.org
Arid regions (or drylands) cover about 45% of Earth's land surface; in most classifications of
ecosystem types, they constitute the largest biome on the planet. Yet the global change …
ecosystem types, they constitute the largest biome on the planet. Yet the global change …
Tuberculosis, pulmonary cavitation, and matrix metalloproteinases
CWM Ong, PT Elkington, JS Friedland - American journal of …, 2014 - atsjournals.org
Tuberculosis (TB), a chronic infectious disease of global importance, is facing the
emergence of drug-resistant strains with few new drugs to treat the infection. Pulmonary …
emergence of drug-resistant strains with few new drugs to treat the infection. Pulmonary …
Immunity and immunopathology in the tuberculous granuloma
AJ Pagán, L Ramakrishnan - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Granulomas, organized aggregates of immune cells, are a defining feature of tuberculosis
(TB). Granuloma formation is implicated in the pathogenesis of a variety of inflammatory …
(TB). Granuloma formation is implicated in the pathogenesis of a variety of inflammatory …