Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Mesenchymal stem cells (MSCs) are emerging as a promising therapeutic approach of cell-
based therapy for a wide range of autoimmune disorders and degenerative diseases. In …

Background Spinal cord injury (SCI) can lead to severe motor and sensory dysfunction with
high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano …

Mammalian mesenchymal stem cells (MSCs) have been shown to be strongly
immunosuppressive in both animal disease models and human clinical trials. We have …

There are more than one million patients worldwide suffering paralysis caused by spinal
cord injury (SCI). SCI causes severe socioeconomic problems not only to the patients and …

Spinal cord injury (SCI) is an as yet untreatable neuropathology that causes severe
dysfunction and disability. Cell-based therapies hold neuroregenerative and neuroprotective …

The incidence of acute and chronic spinal cord injury (SCI) in the United States is more than
10,000 per year, resulting in 720 cases per million persons enduring permanent disability …

BACKGROUND: In our previous report, 3 of 10 patients with spinal cord injury who were
injected with autologous mesenchymal stem cells (MSCs) showed motor improvement in the …

Significant progress has been made during the past decade towards the clinical adoption of
cell-based therapeutics. However, existing cell-delivery approaches have shown limited …

Numerous strategies have been managed to improve functional recovery after spinal cord
injury (SCI) but an optimal strategy doesn't exist yet. Actually, it is the complexity of the …