Advances in injectable hydrogel strategies for heart failure treatment
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …
public health problem surpassing cancer and urgently needs to be solved. According to the …
The soft-and hard-heartedness of cardiac fibroblasts: mechanotransduction signaling pathways in fibrosis of the heart
Cardiac fibrosis, the excessive accumulation of extracellular matrix (ECM), remains an
unresolved problem in most forms of heart disease. In order to be successful in preventing …
unresolved problem in most forms of heart disease. In order to be successful in preventing …
Injectable granular hydrogels with multifunctional properties for biomedical applications
JE Mealy, JJ Chung, HH Jeong, D Issadore… - Advanced …, 2018 - Wiley Online Library
Injectable hydrogels are useful for numerous biomedical applications, such as to introduce
therapeutics into tissues or for 3D printing. To expand the complexity of available injectable …
therapeutics into tissues or for 3D printing. To expand the complexity of available injectable …
[HTML][HTML] An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction
L Zhang, Z Bei, T Li, Z Qian - Bioactive Materials, 2023 - Elsevier
Myocardial infarction (MI) causes irreversible damage to the heart muscle, seriously
threatening the lives of patients. Injectable hydrogels have attracted extensive attention in …
threatening the lives of patients. Injectable hydrogels have attracted extensive attention in …
Myocardial‐infarction‐responsive smart hydrogels targeting matrix metalloproteinase for on‐demand growth factor delivery
C Fan, J Shi, Y Zhuang, L Zhang, L Huang… - Advanced …, 2019 - Wiley Online Library
Although in situ restoration of blood supply to the infarction region and attenuating pre‐
existing extracellular matrix degradation remain potential therapeutic approaches for …
existing extracellular matrix degradation remain potential therapeutic approaches for …
Reactive oxygen species scavenging with a biodegradable, thermally responsive hydrogel compatible with soft tissue injection
Tissue damage and the impairment of regenerative processes by excessive reactive oxygen
species (ROS) contributes to the pathogenesis of various diseases in soft tissues including …
species (ROS) contributes to the pathogenesis of various diseases in soft tissues including …
Hydrogel based approaches for cardiac tissue engineering
Heart failure still represents the leading cause of death worldwide. Novel strategies using
stem cells and growth factors have been investigated for effective cardiac tissue …
stem cells and growth factors have been investigated for effective cardiac tissue …
Role of biomaterials in cardiac repair and regeneration: therapeutic intervention for myocardial infarction
Heart failure or myocardial infarction (MI) is one of the world's leading causes of death. Post
MI, the heart can develop pathological conditions such as ischemia, inflammation, fibrosis …
MI, the heart can develop pathological conditions such as ischemia, inflammation, fibrosis …
Antifibrotic therapies to control cardiac fibrosis
Z Fan, J Guan - Biomaterials research, 2016 - spj.science.org
Cardiac fibrosis occurs naturally after myocardial infarction. While the initially formed fibrotic
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …
An injectable oxygen release system to augment cell survival and promote cardiac repair following myocardial infarction
Oxygen deficiency after myocardial infarction (MI) leads to massive cardiac cell death.
Protection of cardiac cells and promotion of cardiac repair are key therapeutic goals. These …
Protection of cardiac cells and promotion of cardiac repair are key therapeutic goals. These …