SUMMARY Herpes simplex virus 1 (HSV-1) is very successful in establishing acute and
latent infections in humans by counteracting host antiviral innate immune responses. HSV-1 …

Viruses are fully reliant on the translation machinery of their host cells to produce the
polypeptides that are essential for viral replication. Consequently, viruses recruit host …

Coronaviruses have large positive-strand RNA genomes that are 5′ capped and 3′
polyadenylated. The 5′-terminal two-thirds of the genome contain two open reading frames …

Gastroenteritis is among the leading causes of mortality globally in infants and young
children, with rotavirus (RV) causing~ 258 million episodes of diarrhea and~ 128,000 deaths …

As obligate intracellular parasites, virus reproduction requires host cell functions. Despite
variations in genome size and configuration, nucleic acid composition, and their repertoire of …

Viruses are obligate intracellular parasites, and their replication requires host cell functions.
Although the size, composition, complexity, and functions encoded by their genomes are …

Viral infection triggers the activation of antiviral innate immune responses in mammalian
cells. Viral RNA in the cytoplasm activates signaling pathways that result in the production of …

Background eIF2α is a regulatory node that controls protein synthesis initiation by its
phosphorylation or dephosphorylation. General control nonderepressible-2 (GCN2), protein …

Processing bodies (PBs) and Stress Granules (SGs) are the founding members of a new
class of RNA granules, known as mRNA silencing foci, as they harbour transcripts …

Virus infection initiates a number of cellular stress responses that modulate gene regulation
and compartmentalization of RNA. Viruses must control host gene expression and the …