Emerging role of carbonic anhydrase inhibitors
CT Supuran - Clinical Science, 2021 - portlandpress.com
Inhibition of carbonic anhydrase (CA, EC 4.2. 1.1) was clinically exploited for decades, as
most modern diuretics were obtained considering as lead molecule acetazolamide, the …
most modern diuretics were obtained considering as lead molecule acetazolamide, the …
Engineered living materials: prospects and challenges for using biological systems to direct the assembly of smart materials
PQ Nguyen, NMD Courchesne… - Advanced …, 2018 - Wiley Online Library
Vast potential exists for the development of novel, engineered platforms that manipulate
biology for the production of programmed advanced materials. Such systems would possess …
biology for the production of programmed advanced materials. Such systems would possess …
A stony coral cell atlas illuminates the molecular and cellular basis of coral symbiosis, calcification, and immunity
S Levy, A Elek, X Grau-Bové, S Menéndez-Bravo… - Cell, 2021 - cell.com
Stony corals are colonial cnidarians that sustain the most biodiverse marine ecosystems on
Earth: coral reefs. Despite their ecological importance, little is known about the cell types …
Earth: coral reefs. Despite their ecological importance, little is known about the cell types …
A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation
CT Supuran - Bioorganic & Medicinal Chemistry Letters, 2023 - Elsevier
Advances in the carbonic anhydrase (CA, EC 4.2. 1.1) research over the last three decades
are presented, with an emphasis on the deciphering of the activation mechanism, the …
are presented, with an emphasis on the deciphering of the activation mechanism, the …
Antioxidant and anticholinergic properties of olivetol
P Taslimi, İ Gulçin - Journal of food biochemistry, 2018 - Wiley Online Library
Olivetol is a pioneer in diverse syntheses of tetrahydrocannabinol. It is produced by a type of
insects, which is used as a pheromone, antiseptic, or repellent agent. In this study, we …
insects, which is used as a pheromone, antiseptic, or repellent agent. In this study, we …
Geochemical negative emissions technologies: Part I. Review
Over the previous two decades, a diverse array of geochemical negative emissions
technologies (NETs) have been proposed, which use alkaline minerals for removing and …
technologies (NETs) have been proposed, which use alkaline minerals for removing and …
Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase
Inorganic anions inhibit the metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1) generally
by coordinating to the active site metal ion. Cyanate was reported as a non-coordinating CA …
by coordinating to the active site metal ion. Cyanate was reported as a non-coordinating CA …
Coral host cells acidify symbiotic algal microenvironment to promote photosynthesis
Symbiotic dinoflagellate algae residing inside coral tissues supply the host with the majority
of their energy requirements through the translocation of photosynthetically fixed carbon …
of their energy requirements through the translocation of photosynthetically fixed carbon …
Comparative genomics explains the evolutionary success of reef-forming corals
Transcriptome and genome data from twenty stony coral species and a selection of
reference bilaterians were studied to elucidate coral evolutionary history. We identified …
reference bilaterians were studied to elucidate coral evolutionary history. We identified …
Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors
G De Simone, V Alterio, CT Supuran - Expert opinion on drug …, 2013 - Taylor & Francis
Introduction: Carbonic anhydrases (CAs, EC 4.2. 1.1) exist as five genetically distinct
families (α, β, γ, δ and ζ) in organisms all over the phylogenetic tree. Due to the ubiquity of …
families (α, β, γ, δ and ζ) in organisms all over the phylogenetic tree. Due to the ubiquity of …