Cell type–and brain region–resolved mouse brain proteome

K Sharma, S Schmitt, CG Bergner, S Tyanova… - Nature …, 2015 - nature.com
Brain transcriptome and connectome maps are being generated, but an equivalent effort on
the proteome is currently lacking. We performed high-resolution mass spectrometry–based …

Estrogen and female reproductive tract innervation: cellular and molecular mechanisms of autonomic neuroplasticity

MM Brauer, PG Smith - Autonomic Neuroscience, 2015 - Elsevier
The female reproductive tract undergoes remarkable functional and structural changes
associated with cycling, conception and pregnancy, and it is likely advantageous to both …

Structure/function relationships of axon-associated adhesion receptors of the immunoglobulin superfamily

T Brümmendorf, FG Rathjen - Current opinion in neurobiology, 1996 - Elsevier
Evidence is accumulating that axonal members of the Ig superfamily (IgSF) interact in a
complex manner with other axonal Ig-like proteins and with proteins of the extracellular …

Long neural genes harbor recurrent DNA break clusters in neural stem/progenitor cells

PC Wei, AN Chang, J Kao, Z Du, RM Meyers, FW Alt… - Cell, 2016 - cell.com
Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for
neural development, and brain cells frequently contain somatic genomic variations that …

Transcriptomic profiling of the developing cardiac conduction system at single-cell resolution

WR Goodyer, BM Beyersdorf, DT Paik, L Tian… - Circulation …, 2019 - Am Heart Assoc
Rationale: The cardiac conduction system (CCS) consists of distinct components including
the sinoatrial node, atrioventricular node, His bundle, bundle branches, and Purkinje fibers …

The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells*♦

SE Hiemer, AD Szymaniak, X Varelas - Journal of Biological Chemistry, 2014 - ASBMB
Uncontrolled transforming growth factor-β (TGFβ) signaling promotes aggressive metastatic
properties in late-stage breast cancers. However, how TGFβ-mediated cues are directed to …

The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells

D Choi, L Montermini, DK Kim, B Meehan… - Molecular & Cellular …, 2018 - ASBMB
Glioblastoma multiforme (GBM) is a highly aggressive and heterogeneous form of primary
brain tumors, driven by a complex repertoire of oncogenic alterations, including the …

TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein-tyrosine phosphatase-ζ/β, and N-CAM

P Milev, P Maurel, M Häring, RK Margolis… - Journal of Biological …, 1996 - ASBMB
Proteoglycans appear to play an important role in modulating cell-cell and cell-matrix
interactions during nervous tissue histogenesis. The nervous tissue-specific chondroitin …

The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting

AF Pimenta, V Zhukareva, MF Barbe, BS Reinoso… - Neuron, 1995 - cell.com
The formation of brain circuits requires molecular recognition between functionally related
neurons. We report the cloning of a molecule that participates in these interactions. The …

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans

M Zhang, F Song, L Liang, H Nan… - Human molecular …, 2013 - academic.oup.com
Aiming to identify novel genetic loci for pigmentation and skin cancer, we conducted a series
of genome-wide association studies on hair color, eye color, number of sunburns, tanning …