Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease

G De Rubis, KR Paudel, L Corrie, S Mehndiratta… - Naunyn-Schmiedeberg's …, 2024 - Springer
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …

Engineered liposomes in interventional theranostics of solid tumors

N Kommineni, R Chaudhari, J Conde… - ACS Biomaterials …, 2023 - ACS Publications
Engineered liposomal nanoparticles have unique characteristics as cargo carriers in cancer
care and therapeutics. Liposomal theranostics have shown significant progress in preclinical …

Interplay of gut microbiota in polycystic ovarian syndrome: role of gut microbiota, mechanistic pathways and potential treatment strategies

L Corrie, A Awasthi, J Kaur, S Vishwas, M Gulati… - Pharmaceuticals, 2023 - mdpi.com
Polycystic Ovarian Syndrome (PCOS) comprises a set of symptoms that pose significant risk
factors for various diseases, including type 2 diabetes, cardiovascular disease, and cancer …

Application of quality by design in optimization of nanoformulations: Principle, perspectives and practices

D Birla, N Khandale, B Bashir, M ShahbazAlam… - Drug Delivery and …, 2024 - Springer
Nanoparticulate drug delivery systems (NDDS) based nanoformulations have emerged as
promising drug delivery systems. Various NDDS-based formulations have been reported …

HPMCAS-Based Amorphous Solid Dispersions in Clinic: A Review on Manufacturing Techniques (Hot Melt Extrusion and Spray Drying), Marketed Products and …

L Corrie, S Ajjarapu, S Banda, M Parvathaneni… - Materials, 2023 - mdpi.com
Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …

Raspberry ketone loaded self nanoemulsifying system of cardamom oil: Assessment of phase behavior, dissolution rate and anti-hyperlipidemic activity

A Kumar, K Shipam, S Kumar - Journal of Drug Delivery Science and …, 2024 - Elsevier
Raspberry ketone (RK), a polyphenolic antioxidant, possesses free radical scavenging
against oxidative species and has potential of anti-inflammatory, anti-proliferative and anti …

Polysaccharide-fecal microbiota-based colon-targeted self-nanoemulsifying drug delivery system of curcumin for treating polycystic ovarian syndrome

L Corrie, H Singh, M Gulati, S Vishwas… - Naunyn-Schmiedeberg's …, 2024 - Springer
The gut microbiome is involved in the pathogenesis of many diseases including polycystic
ovarian syndrome (PCOS). Modulating the gut microbiome can lead to eubiosis and …

DOPE/CHEMS-based EGFR-targeted immunoliposomes for docetaxel delivery: formulation development, physicochemical characterization and biological evaluation …

TS Moreira, ADO Silva, BRF Vasconcelos, ES Santos… - Pharmaceutics, 2023 - mdpi.com
Docetaxel (DTX) is a non-selective antineoplastic agent with low solubility and a series of
side effects. The technology of pH-sensitive and anti-epidermal growth factor receptor (anti …

Enhancing the Topical Antibacterial Activity of Fusidic Acid via Embedding into Cinnamon Oil Nano-Lipid Carrier

HS Elsewedy, TM Shehata, SM Genedy, KM Siddiq… - Gels, 2024 - mdpi.com
Presently, antimicrobial resistance is of great risk to remarkable improvements in health
conditions and infection management. Resistance to various antibiotics has been …

Physicochemical and in vitro digestion properties of curcumin-loaded solid lipid nanoparticles with different solid lipids and emulsifiers

Y Yu, D Chen, YY Lee, N Chen, Y Wang, C Qiu - Foods, 2023 - mdpi.com
Curcumin-loaded solid lipid nanoparticles (Cur-SLN) were prepared using medium-and
long chain diacylglycerol (MLCD) or glycerol tripalmitate (TP) as lipid matrix and three kinds …