Peptoids and polypeptoids at the frontier of supra-and macromolecular engineering
In most general terms, polymers and their supramolecular assemblies have been defining
life on this planet since its conception. Polymers of nucleic acids carry the code of life and …
life on this planet since its conception. Polymers of nucleic acids carry the code of life and …
Polysarcosine-containing copolymers: Synthesis, characterization, self-assembly, and applications
Although the first polysarcosine (pSar) synthesis by Wesseley et al. was reported almost a
century ago, it was only recently that pSar gained broader attention and is considered a …
century ago, it was only recently that pSar gained broader attention and is considered a …
Peptoid polymers: a highly designable bioinspired material
J Sun, RN Zuckermann - ACS nano, 2013 - ACS Publications
Bioinspired polymeric materials are attracting increasing attention due to significant
advantages over their natural counterparts: the ability to precisely tune their structures over a …
advantages over their natural counterparts: the ability to precisely tune their structures over a …
Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
NP Chongsiriwatana, JA Patch… - Proceedings of the …, 2008 - National Acad Sciences
Antimicrobial peptides (AMPs) and their mimics are emerging as promising antibiotic agents.
We present a library of “ampetoids”(antimicrobial peptoid oligomers) with helical structures …
We present a library of “ampetoids”(antimicrobial peptoid oligomers) with helical structures …
Recent progress in the design of monodisperse, sequence‐defined macromolecules
SC Solleder, RV Schneider, KS Wetzel… - Macromolecular …, 2017 - Wiley Online Library
This review describes different synthetic strategies towards sequence‐defined,
monodisperse macromolecules, which are built up by iterative approaches and lead to …
monodisperse macromolecules, which are built up by iterative approaches and lead to …
Sequence programmable peptoid polymers for diverse materials applications
Polymer sequence programmability is required for the diverse structures and complex
properties that are achieved by native biological polymers, but efforts towards controlling the …
properties that are achieved by native biological polymers, but efforts towards controlling the …
Peptoid origins
RN Zuckermann - Peptide Science, 2011 - Wiley Online Library
Peptoid oligomers were initially developed as part of a larger basic research effort to
accelerate the drug‐discovery process in the biotech/biopharma industry. Their ease of …
accelerate the drug‐discovery process in the biotech/biopharma industry. Their ease of …
Solid-Phase Synthesis of N-Substituted Glycine Oligomers (α-Peptoids) and Derivatives
AS Culf, RJ Ouellette - Molecules, 2010 - mdpi.com
Peptoids (N-substituted polyglycines and extended peptoids with variant backbone amino-
acid monomer units) are oligomeric synthetic polymers that are becoming a valuable …
acid monomer units) are oligomeric synthetic polymers that are becoming a valuable …
Iterative Synthesis of Stereo‐ and Sequence‐Defined Polymers via Acid‐Orthogonal Deprotection Chemistry
Absolute control over polymer stereo‐and sequence structure is highly challenging in
polymer chemistry. Here, an acid‐orthogonal deprotection strategy is proposed for the …
polymer chemistry. Here, an acid‐orthogonal deprotection strategy is proposed for the …
Biomimetic nanostructures: Creating a high-affinity zinc-binding site in a folded nonbiological polymer
BC Lee, TK Chu, KA Dill… - Journal of the American …, 2008 - ACS Publications
One of the long-term goals in developing advanced biomaterials is to generate protein-like
nanostructures and functions from a completely nonnatural polymer. Toward that end, we …
nanostructures and functions from a completely nonnatural polymer. Toward that end, we …