Fused pyrimidines scaffolds such as pyrimidopyrimidines, purines and xanthines are
important structural motifs found in various natural products and drug molecules. They are …

Xanthine is the most ubiquitous heterocyclic aromatic compound and have attracted much
synthetic interest due to their numerous pharmacological activities. It is one of the principal …

Xanthine and its derivatives are considered a pharmacologically potential moiety that
manifests immense biological activities. Owing to this much diversity in the biological field …

Xanthine and its derivatives belong to the class of purine alkaloids. They are natural bases
holding nitrogen atoms within the molecular structure, and they have an effective …

In the past many research studies have focused on the thiazolidine-4-one scaffold, due to
the important biological effects associated with its heterocycle. This scaffold is present in the …

Asthma is a chronic obstructive pulmonary disease which affects the bronchi airways and
results in the inflammation of bronchioles along with the hyper‐responsiveness to some …

Materials and methods. Melting points were determined using capillary method on DMP (M).
1Н NMR-spectra were recorded by Varian Mercury VX-200 device (company «Varian» …

Background Asthma is the most common chronic respiratory disease in childhood. However,
it is quite difficult to make a prompt diagnosis of asthma in a child 5 years and younger …

Актуальность темы. Сесквитерпеновые лактоны–обширная группа соединений,
встречающихся в различных представителях растений семейства сложноцветные …

Aim. Selection of basic compounds is a key moment of the novel drug substances
development process. Nowadays, it is possible to model the properties of biologically active …