[HTML][HTML] Indocyanine green-incorporating nanoparticles for cancer theranostics

H Wang, X Li, BWC Tse, H Yang, CA Thorling, Y Liu… - Theranostics, 2018 - ncbi.nlm.nih.gov
Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal
angiography, and defining cardiovascular and liver function for over 50 years. Recently …

NIR fluorescence-guided tumor surgery: new strategies for the use of indocyanine green

C Egloff-Juras, L Bezdetnaya, G Dolivet… - International journal of …, 2019 - Taylor & Francis
Surgery is the frontline treatment for a large number of cancers. The objective of these
excisional surgeries is the complete removal of the primary tumor with sufficient safety …

ER-targeting PDT converts tumors into in situ therapeutic tumor vaccines

X Liu, Y Liu, X Li, J Huang, X Guo, J Zhang, Z Luo… - Acs Nano, 2022 - ACS Publications
A therapeutic tumor vaccine is a promising approach to cancer treatment. One of its
strategies is to treat patient-derived tumor cells in vitro and then administer them in vivo to …

Quantitative assessment of nanoparticle biodistribution by fluorescence imaging, revisited

F Meng, J Wang, Q Ping, Y Yeo - ACS nano, 2018 - ACS Publications
Fluorescence-based whole-body imaging is widely used in the evaluation of nanoparticles
(NPs) in small animals, often combined with quantitative analysis to indicate their …

pH‐Responsive β‐Glucans‐Complexed mRNA in LNPs as an Oral Vaccine for Enhancing Cancer Immunotherapy

PK Luo, HM Ho, MC Chiang, LA Chu… - Advanced …, 2024 - Wiley Online Library
Abstract mRNA vaccines for cancer immunotherapy are commonly delivered using lipid
nanoparticles (LNPs), which, when administered intravenously, may accumulate in the liver …

Measuring particle size distribution by asymmetric flow field flow fractionation: a powerful method for the preclinical characterization of lipid-based nanoparticles

F Caputo, A Arnould, M Bacia, WL Ling… - Molecular …, 2019 - ACS Publications
Particle size distribution and stability are key attributes for the evaluation of the safety and
efficacy profile of medical nanoparticles (Med-NPs). Measuring particle average size and …

Hyaluronic acid-based M1 macrophage targeting and environmental responsive drug releasing nanoparticle for enhanced treatment of rheumatoid arthritis

P Wang, Y Zhang, H Lei, J Yu, Q Zhou, X Shi… - Carbohydrate …, 2023 - Elsevier
Herein, hyaluronic acid (HA) and β-cyclodextrin (β-CD) is used to form targeted drug
delivery platform HCPC/DEX NPs with previously prepared carbon dots (CDs) as cross …

[HTML][HTML] Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice

R Bouchaala, L Mercier, B Andreiuk, Y Mély… - Journal of controlled …, 2016 - Elsevier
Lipid nanocarriers are considered as promising candidates for drug delivery and cancer
targeting because of their low toxicity, biodegradability and capacity to encapsulate drugs …

In vivo fate of lipid-based nanoparticles

J Qi, J Zhuang, Y Lu, X Dong, W Zhao, W Wu - Drug Discovery Today, 2017 - Elsevier
Highlights•LBNs are readily degradable through lipolysis by lipases.•LBNs that survive
lipolysis can be translocated to various organs and tissues.•Lipid composition, particle size …

In vivo fate of targeted drug delivery carriers

F Zhao, J Wang, Y Zhang, J Hu, C Li, S Liu… - International Journal …, 2024 - Taylor & Francis
This review aimed to systematically investigate the intracellular and subcellular fate of
various types of targeting carriers. Upon entering the body via intravenous injection or other …