Iron is an essential element for virtually all organisms. On the one hand, it facilitates cell
proliferation and growth. On the other hand, iron may be detrimental due to its redox …

Iron is an essential nutrient that facilitates cell proliferation and growth. However, iron also
has the capacity to engage in redox cycling and free radical formation. Therefore, iron can …

New and provocative insights into the relationships between iron and cancer have been
uncovered in recent years. These include delineation of connections that link cellular iron to …

Evidence for the potent influence of stromal organization and function on invasion and
metastasis of breast tumors is ever growing. We have performed a rigorous examination of …

Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …

Lipocalin-2 (LCN2) is a secreted glycoprotein linked to several physiological roles, including
transporting hydrophobic ligands across cell membranes, modulating immune responses …

Objective Sepsis is the most common trigger for acute kidney injury (AKI) in critically ill
patients. We sought to determine whether there are unique patterns to plasma and urine …

Background and objectives: Several molecular forms of human neutrophil
lipocalin/neutrophil gelatinase-associated lipocalin (HNL/NGAL), a novel biomarker for …

Survival and recurrence rates in breast cancer are variable for common diagnoses, and
therefore the biological underpinnings of the disease that determine those outcomes are yet …

Here, we report that lipocalin 2 (Lcn2) promotes breast cancer progression, and we identify
the mechanisms underlying this function. We first found that Lcn2 levels were consistently …