Circadian rhythm disturbances in mood disorders: insights into the role of the suprachiasmatic nucleus

CA Vadnie, CA McClung - Neural plasticity, 2017 - Wiley Online Library
Circadian rhythm disturbances are a common symptom among individuals with mood
disorders. The suprachiasmatic nucleus (SCN), in the ventral part of the anterior …

Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: a critical multi‐disciplinary literature review and agenda for future …

MJ McCarthy, JF Gottlieb, R Gonzalez… - Bipolar …, 2022 - Wiley Online Library
Aim Symptoms of bipolar disorder (BD) include changes in mood, activity, energy, sleep,
and appetite. Since many of these processes are regulated by circadian function, circadian …

Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation

S Chung, EJ Lee, S Yun, HK Choe, SB Park, HJ Son… - Cell, 2014 - cell.com
The circadian nature of mood and its dysfunction in affective disorders is well recognized,
but the underlying molecular mechanisms are still unclear. Here, we show that the circadian …

Clock genes and altered sleep–wake rhythms: their role in the development of psychiatric disorders

A Charrier, B Olliac, P Roubertoux… - International journal of …, 2017 - mdpi.com
In mammals, the circadian clocks network (central and peripheral oscillators) controls
circadian rhythms and orchestrates the expression of a range of downstream genes …

Neuronal correlates of depression

D Chaudhury, H Liu, MH Han - Cellular and Molecular Life Sciences, 2015 - Springer
Major depressive disorder (MDD) is a common psychiatric disorder effecting approximately
121 million people worldwide and recent reports from the World Health Organization (WHO) …

Access to daylight at home improves circadian alignment, sleep, and mental health in healthy adults: A crossover study

R Nagare, M Woo, P MacNaughton, B Plitnick… - International journal of …, 2021 - mdpi.com
As the primary environmental cue for the body's master biological clock, light–dark patterns
are key for circadian alignment and are ultimately fundamental to multiple dimensions of …

Circadian modulation of dopamine levels and dopaminergic neuron development contributes to attention deficiency and hyperactive behavior

J Huang, Z Zhong, M Wang, X Chen, Y Tan… - Journal of …, 2015 - Soc Neuroscience
Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent psychiatric
disorders in children and adults. While ADHD patients often display circadian abnormalities …

Effects of a psychedelic 5-HT2A receptor agonist on anxiety-related behavior and fear processing in mice

BD Pędzich, S Rubens, M Sekssaoui, A Pierre… - …, 2022 - nature.com
Psychedelic-assisted psychotherapy gained considerable interest as a novel treatment
strategy for fear-related mental disorders but the underlying mechanism remains poorly …

NLRP3 inflammasome activation contributes to long-term behavioral alterations in mice injected with lipopolysaccharide

W Zhu, FS Cao, J Feng, HW Chen, JR Wan, Q Lu… - Neuroscience, 2017 - Elsevier
Lipopolysaccharide (LPS) might affect the central nervous system by causing
neuroinflammation, which subsequently leads to brain damage and dysfunction. In this …

Circadian rhythms and substance use disorders: A bidirectional relationship

EK Tamura, KS Oliveira-Silva… - Pharmacology …, 2021 - Elsevier
The circadian system organizes circadian rhythms (biological cycles that occur around 24 h)
that couple environmental cues (zeitgebers) with internal functions of the organism. The …