Natural products play a critical role in the discovery and development of numerous drugs for
the treatment of various types of cancer. These phytochemicals have demonstrated anti …

Curcumin (diferuloylmethane) is the main constituent extracted from turmeric. This
polyphenol is a non-toxic, potent compound with anticancer, anti-inflammatory, antibacterial …

Conventional photocages only respond to short wavelength light, which is a significant
obstacle to developing efficient phototherapy in vivo. The development of photocages …

Serum and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that works
under acute transcriptional control by several stimuli, including serum and glucocorticoids. It …

Microtubule affinity-regulating kinase (MARK4) plays a key role in Alzheimer's disease (AD)
development as its overexpression is directly linked to increased tau phosphorylation …

Protein as a carrier to improve the solubility and bioavailability of curcumin has been studied
widely. However, to date the researches were mainly focused on its binding mechanism and …

Design and development of potential pyruvate dehydrogenase kinase 3 (PDK3) inhibitors
have gained attention because of their possible therapeutic uses in lung cancer therapy. In …

Microtubule affinity-regulating kinase 4 (MARK4) has recently been identified as a potential
drug target for several complex diseases including cancer, diabetes and neurodegenerative …

To improve phospholipid bilayer membrane stability and reduce degradation of
encapsulated curcumin, liposomes coated with guar gum (GG) and cationic guar gum (CGG) …

Abstract Pyruvate dehydrogenase kinase 3 (PDK3) is a mitochondrial protein, has recently
been considered as a potential pharmacological target for varying types of cancer. Here, we …