The purpose of the present study was to clarify whether the precipitation profile of a drug in
bicarbonate buffer (BCB) may differ from that in phosphate buffer (PPB) by a well-controlled …

Purpose The pharmaceutical literature contains examples wherein desupersaturation from
high concentrations does not proceed to equilibrium concentration of the thermodynamically …

无定形固体分散体是提高难溶性药物生物利用度最有效的策略之一, 但其易受到处方因素,
制备工艺, 存储条件和溶出条件等因素的影响从而在储存期或溶出过程中结晶, 丧失溶出优势 …