Pathogenesis of SARS-CoV-2 and Mycobacterium tuberculosis Coinfection
Coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, is an infectious disease
that poses severe threats to global public health and significant economic losses. The …
that poses severe threats to global public health and significant economic losses. The …
Macrophage nuclear receptors: Emerging key players in infectious diseases
CM Leopold Wager, E Arnett, LS Schlesinger - PLoS pathogens, 2019 - journals.plos.org
Nuclear receptors (NRs) are ligand-activated transcription factors that are expressed in a
variety of cells, including macrophages. For decades, NRs have been therapeutic targets …
variety of cells, including macrophages. For decades, NRs have been therapeutic targets …
Precision vaccine development: cues from natural immunity
Traditional vaccine development against infectious diseases has been guided by the
overarching aim to generate efficacious vaccines normally indicated by an antibody and/or …
overarching aim to generate efficacious vaccines normally indicated by an antibody and/or …
Circ_0001490/miR-579-3p/FSTL1 axis modulates the survival of mycobacteria and the viability, apoptosis and inflammatory response in Mycobacterium tuberculosis …
Q Deng, J Huang, J Yan, E Mao, HJ Chen, C Wang - Tuberculosis, 2021 - Elsevier
Background Macrophages play an important role in the host immune response against
mycobacterial infection, and this process is regulated by various factors, including circular …
mycobacterial infection, and this process is regulated by various factors, including circular …
PPARγ Ameliorates Mycobacterium tuberculosis H37Ra-Induced Foamy Macrophage Formation via the ABCG1-Dependent Cholesterol Efflux Pathway in THP-1 …
Y Ye, J Liu, Y Guo, Y Gao, J Rao, R Su… - Frontiers in …, 2022 - frontiersin.org
Foamy macrophages are present during the course of Mycobacterium tuberculosis (Mtb)
infection and seems to be nutrient-rich reservoir and secure reservoir for the bacilli, which …
infection and seems to be nutrient-rich reservoir and secure reservoir for the bacilli, which …
The impact of aging on the lung alveolar environment, predetermining susceptibility to respiratory infections
Respiratory infections are one of the top causes of death in the elderly population,
displaying susceptibility factors with increasing age that are potentially amenable to …
displaying susceptibility factors with increasing age that are potentially amenable to …
The Peroxisome Proliferator-Activated Receptor α- Agonist Gemfibrozil Promotes Defense Against Mycobacterium abscessus Infections
YS Kim, JK Kim, BTB Hanh, SY Kim, HJ Kim, YJ Kim… - Cells, 2020 - mdpi.com
Peroxisome proliferator-activated receptor α (PPARα) shows promising potential to enhance
host defenses against Mycobacterium tuberculosis infection. Herein we evaluated the …
host defenses against Mycobacterium tuberculosis infection. Herein we evaluated the …
Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria
Abstract Background Bovine TB (bTB), caused by infection with Mycobacterium bovis, is a
major endemic disease affecting global cattle production. The key innate immune cell that …
major endemic disease affecting global cattle production. The key innate immune cell that …
MicroRNA‑502‑3p promotes Mycobacterium tuberculosis survival in macrophages by modulating the inflammatory response by targeting ROCK1
F Liu, Z Dong, Y Lin, H Yang… - Molecular Medicine …, 2021 - spandidos-publications.com
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tuberculosis) infection and
has the highest mortality rate of any single infectious disease worldwide. The aim of the …
has the highest mortality rate of any single infectious disease worldwide. The aim of the …
Rickettsia conorii survival in THP‐1 macrophages involves host lipid droplet alterations and active rickettsial protein production
PE Allen, RC Noland, JJ Martinez - Cellular microbiology, 2021 - Wiley Online Library
Rickettsia conorii is a Gram‐negative, cytosolic intracellular bacterium that has classically
been investigated in terms of endothelial cell infection. However, R. conorii and other human …
been investigated in terms of endothelial cell infection. However, R. conorii and other human …