Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals–a comprehensive review

L Padrela, MA Rodrigues, A Duarte, AMA Dias… - Advanced drug delivery …, 2018 - Elsevier
Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

Solubility, Extraction, and nanoparticles production in supercritical carbon dioxide: A mini‐review

G Sodeifian, MMB Usefi - ChemBioEng Reviews, 2023 - Wiley Online Library
Supercritical carbon dioxide (SC‐CO2) is CO2 that is stored beyond its critical point of 7.4
MPa and 31.1° C. Given the request for consumption of a green solvent for the environment …

Orally deliverable sequence-targeted astaxanthin nanoparticles for colitis alleviation

Y Chen, W Su, S Tie, W Cui, X Yu, L Zhang, Z Hua… - Biomaterials, 2023 - Elsevier
Orally targeted strategy of anti-inflammatory agents has attracted tremendous attention for
reducing highly health-care costs and enhancing the intervention efficiency of ulcerative …

Zein/soluble soybean polysaccharide composite nanoparticles for encapsulation and oral delivery of lutein

H Li, Y Yuan, J Zhu, T Wang, D Wang, Y Xu - Food Hydrocolloids, 2020 - Elsevier
In this work, zein/soluble soybean polysaccharide (SSPS) composite nanoparticles were
fabricated using a facile antisolvent precipitation method to encapsulate lutein. The ternary …

Recent advances in nanoencapsulation of hydrophobic marine bioactives: Bioavailability, safety, and sensory attributes of nano-fortified functional foods

SF Hosseini, L Ramezanzade… - Trends in Food Science & …, 2021 - Elsevier
Background There is increasing demand from consumers for more natural foods with
potential health benefits. The marine environment is an abundant source of potentially …

Solubility measurement of verapamil for the preparation of developed nanomedicines using supercritical fluid

N Esfandiari, N Saadati Ardestani, RS Alwi, A Rojas… - Scientific Reports, 2023 - nature.com
A static method is employed to determine the solubilities of verapamil in supercritical carbon
dioxide (SC-CO2) at temperatures between 308 and 338 K and pressures between 12 and …

Advances of astaxanthin-based delivery systems for precision nutrition

Y Chen, W Su, S Tie, L Zhang, M Tan - Trends in Food Science & …, 2022 - Elsevier
Background Astaxanthin is a marine carotenoid which has received widely attention due to
its strongly functional activity in food industry. However, the poor water solubility and …

High-pressure fluid technologies: Recent approaches to the production of natural pigments for food and pharmaceutical applications

AAF Zielinski, A del Pilar Sanchez-Camargo… - Trends in Food Science …, 2021 - Elsevier
Background Color is the first and most impacting attribute affecting directly the consumers
preference, selection, and desire. Synthetic colorant ingredients are largely used by the food …

An investigation into Sunitinib malate nanoparticle production by US-RESOLV method: Effect of type of polymer on dissolution rate and particle size distribution

F Razmimanesh, G Sodeifian, SA Sajadian - The Journal of Supercritical …, 2021 - Elsevier
The present study practiced ultrasonic-assisted rapid expansion of a supercritical CO 2
solution into a liquid solvent (US-RESOLV) process for the synthesis of nanoparticles (NPs) …

Effect of Ca2+ cross-linking on the properties and structure of lutein-loaded sodium alginate hydrogels

P Xu, J Song, Z Dai, Y Xu, D Li, C Wu - International Journal of Biological …, 2021 - Elsevier
In order to construct nano-lutein hydrogels with sustained release properties, the basic
properties and structure of nano-lutein hydrogels cross-linked with different concentrations …