The super-donor phenomenon in fecal microbiota transplantation

BC Wilson, T Vatanen, WS Cutfield… - Frontiers in cellular and …, 2019 - frontiersin.org
Fecal microbiota transplantation (FMT) has become a highly effective bacteriotherapy for
recurrent Clostridium difficile infection. Meanwhile the efficacy of FMT for treating chronic …

Fecal transplantation for treatment of inflammatory bowel disease

A Imdad, NG Pandit, M Zaman… - Cochrane Database …, 2023 - cochranelibrary.com
Background Inflammatory bowel disease (IBD) is a chronic, relapsing disease of the
gastrointestinal (GI) tract that is thought to be associated with a complex interplay between …

Systematic review with meta‐analysis: faecal microbiota transplantation for the induction of remission for active ulcerative colitis

SP Costello, W Soo, RV Bryant, V Jairath… - Alimentary …, 2017 - Wiley Online Library
Background Faecal microbiota transplantation (FMT) is emerging as a novel therapy for
ulcerative colitis (UC). Interpretation of efficacy of FMT for UC is complicated by differences …

Systematic review and meta-analysis: fecal microbiota transplantation for treatment of active ulcerative colitis

N Narula, Z Kassam, Y Yuan… - Inflammatory bowel …, 2017 - academic.oup.com
Background Changes in the colonic microbiota may play a role in the pathogenesis of
ulcerative colitis (UC) and restoration of healthy gut microbiota may ameliorate disease. A …

An ecological framework to understand the efficacy of fecal microbiota transplantation

Y Xiao, MT Angulo, S Lao, ST Weiss, YY Liu - Nature communications, 2020 - nature.com
Human gut microbiota plays critical roles in physiology and disease. Our understanding of
ecological principles that govern the dynamics and resilience of this highly complex …

Protocol for fecal microbiota transplantation in inflammatory bowel disease: a systematic review and meta‐analysis

H Fang, L Fu, J Wang - BioMed research international, 2018 - Wiley Online Library
Background. Fecal microbiota transplantation (FMT) is an emerging treatment approach for
inflammatory bowel disease (IBD). The donor selection, the separation of fecal bacteria, the …

The chemistry of gut microbiome in health and diseases

AWY Lau, LTH Tan, NS Ab Mutalib… - Progress In Microbes …, 2021 - hh-publisher.com
There are trillions of microbes residing in our body, with their collective genomes much more
than human genomes. They have been living in a close relationship with us and play a role …

The role of fecal microbiota transplantation in the treatment of inflammatory bowel disease

M Stojek, A Jabłońska, K Adrych - Journal of Clinical Medicine, 2021 - mdpi.com
The exact pathogenesis of inflammatory bowel disease (IBD) is still not completely
understood. It is hypothesized that a genetic predisposition leads to an exaggerated immune …

Matching between donors and ulcerative colitis patients is important for long-term maintenance after fecal microbiota transplantation

K Okahara, D Ishikawa, K Nomura, S Ito… - Journal of clinical …, 2020 - mdpi.com
We previously demonstrated that fresh fecal microbiota transplantation (FMT) following triple
antibiotic therapy (amoxicillin, fosfomycin, metronidazole (AFM); A-FMT) resulted in effective …

Framework for rational donor selection in fecal microbiota transplant clinical trials

C Duvallet, C Zellmer, P Panchal, S Budree… - PLoS …, 2019 - journals.plos.org
Early clinical successes are driving enthusiasm for fecal microbiota transplantation (FMT),
the transfer of healthy gut bacteria through whole stool, as emerging research is linking the …