The state of complement in COVID-19
Hyperactivation of the complement and coagulation systems is recognized as part of the
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
Persistent endotheliopathy in the pathogenesis of long COVID syndrome
H Fogarty, L Townsend, H Morrin… - … of thrombosis and …, 2021 - Wiley Online Library
Background Persistent symptoms including breathlessness, fatigue, and decreased exercise
tolerance have been reported in patients after acute SARS‐CoV‐2 infection. The biological …
tolerance have been reported in patients after acute SARS‐CoV‐2 infection. The biological …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection
A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …
three highly pathogenic variants have emerged in the 21st century. The newest member of …
Severe COVID-19 is a microvascular disease
CJ Lowenstein, SD Solomon - Circulation, 2020 - Am Heart Assoc
P-selectin and VWF are not only stored together in the same granule but also interact to
promote thrombosis. After exocytosis, P-selectin is displayed on the outer surface of the …
promote thrombosis. After exocytosis, P-selectin is displayed on the outer surface of the …
Prolonged elevation of D‐dimer levels in convalescent COVID‐19 patients is independent of the acute phase response
Background Persistent fatigue, breathlessness, and reduced exercise tolerance have been
reported following acute COVID‐19 infection. Although immuno‐thrombosis has been …
reported following acute COVID‐19 infection. Although immuno‐thrombosis has been …
Venous thromboembolism in patients with COVID-19: systematic review and meta-analysis
A Porfidia, E Valeriani, R Pola, E Porreca… - Thrombosis research, 2020 - Elsevier
Background Venous thromboembolism (VTE) may complicate the course of Coronavirus
Disease 2019 (COVID-19). Objectives To evaluate the incidence of VTE in patients with …
Disease 2019 (COVID-19). Objectives To evaluate the incidence of VTE in patients with …
COVID-19 vasculitis and novel vasculitis mimics
COVID-19 has been occasionally linked to histologically confirmed cutaneous vasculitis and
a Kawasaki-like vasculitis, with these entities generally having minimal or no lung …
a Kawasaki-like vasculitis, with these entities generally having minimal or no lung …
[HTML][HTML] SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro
SARS-CoV-2 infection can cause fatal inflammatory lung pathology, including thrombosis
and increased pulmonary vascular permeability leading to edema and hemorrhage. In …
and increased pulmonary vascular permeability leading to edema and hemorrhage. In …