[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport

Z Zhang, Y Lu, J Qi, W Wu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

Nasal vaccination against SARS-CoV-2: Synergistic or alternative to intramuscular vaccines?

M Tiboni, L Casettari, L Illum - International journal of pharmaceutics, 2021 - Elsevier
It is striking that all marketed SARS-CoV-2 vaccines are developed for intramuscular
administration designed to produce humoral and cell mediated immune responses …

Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea

M Unemo, RA Nicholas - Future microbiology, 2012 - Taylor & Francis
The new superbug Neisseria gonorrhoeae has retained resistance to antimicrobials
previously recommended for first-line treatment and has now demonstrated its capacity to …

Current prospects and future challenges for nasal vaccine delivery

H Yusuf, V Kett - Human vaccines & immunotherapeutics, 2017 - Taylor & Francis
Nasal delivery offers many benefits over traditional approaches to vaccine administration.
These include ease of administration without needles that reduces issues associated with …

Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization

CA Fromen, GR Robbins, TW Shen… - Proceedings of the …, 2015 - National Acad Sciences
Pulmonary immunization enhances local humoral and cell-mediated mucosal protection,
which are critical for vaccination against lung-specific pathogens such as influenza or …

Bilosomes in the context of oral immunization: development, challenges and opportunities

A Shukla, V Mishra, P Kesharwani - Drug discovery today, 2016 - Elsevier
Highlights•Bilosomes have emerged as potential tools in oral vaccine delivery.•Bilosomes
can be used in immunization against various diseases.•Orally administered bilosomes can …

A review of non-invasive drug delivery through respiratory routes

YB Zhang, D Xu, L Bai, YM Zhou, H Zhang, YL Cui - Pharmaceutics, 2022 - mdpi.com
With rapid and non-invasive characteristics, the respiratory route of administration has
drawn significant attention compared with the limitations of conventional routes. Respiratory …

A bacteriophage-based, highly efficacious, needle-and adjuvant-free, mucosal COVID-19 vaccine

J Zhu, S Jain, J Sha, H Batra, N Ananthaswamy… - MBio, 2022 - Am Soc Microbiol
ABSTRACT The US Food and Drug Administration-authorized mRNA-and adenovirus-
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …

Mucoadhesive glycol chitosan nanoparticles for intranasal delivery of hepatitis B vaccine: enhancement of mucosal and systemic immune response

D Pawar, KS Jaganathan - Drug delivery, 2016 - Taylor & Francis
In this study, for the first time, glycol chitosan (GC) nanoparticles (NPs) were prepared and
evaluated to obtain systemic and mucosal immune responses against nasally administered …

Can the nasal cavity help tackle COVID-19?

B Pilicheva, R Boyuklieva - Pharmaceutics, 2021 - mdpi.com
Despite the progress made in the fight against the COVID-19 pandemic, it still poses
dramatic challenges for scientists around the world. Various approaches are applied …