Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

Acute kidney injury (AKI) is defined as a decrease in kidney function within hours, which
encompasses both injury and impairment of renal function. AKI is not considered a …

Coptisine, one of the main active components of Rhizoma Coptidis, possesses anti-
inflammatory, antioxidant, anti-apoptosis and renoprotective effects. In this study, we …

Context The effect of kaempferol, a regulator of oestrogen receptors, on atherosclerosis (AS)
and the underlying mechanism is elusive. Objective To explore the effect and mechanism of …

Intervertebral disc degeneration (IDD) is thought to be the primary cause of low back pain, a
severe public health problem worldwide. Current therapy for IDD aims to alleviate the …

Resveratrol (Res) is a polyphenolic compound that has a variety of biological functions and
activities. This study aimed to explore the mechanisms of the antioxidant and proapoptotic …

Cerebral ischemia/reperfusion injury (CIRI) leads to injury in distant organs, most commonly
the lungs, although limited studies have examined self‐protective mechanisms during CIRI …

Acute kidney injury (AKI) represents a complex clinical condition associated with significant
morbidity and mortality. Approximately, 19–33% AKI episodes in hospitalized patients are …

Background Cisplatin is effective against various types of cancers. However, its clinical
application is limited owing to its adverse effects, especially acute kidney injury (AKI) …

Salvianolic acid A (SAA) is a bioactive polyphenol extracted from Salviae miltiorrhizae
Bunge, which possesses a variety of pharmacological activities. In our previous study, we …