Transition metals-catalyzed amination of biomass feedstocks for sustainable construction of N-heterocycles
Q Yan, X Wu, H Jiang, H Wang, F Xu, H Li… - Coordination Chemistry …, 2024 - Elsevier
Transition metals, which are of diversity in their bonding orbitals, have a variety of significant
oxidation states and more complex chemical properties compared to the main group metals …
oxidation states and more complex chemical properties compared to the main group metals …
The use of hoechst dyes for DNA staining and beyond
Hoechst dyes are among the most popular fluorophores used to stain DNA in living and
fixed cells. Moreover, their high affinity and specificity towards DNA make Hoechst dyes …
fixed cells. Moreover, their high affinity and specificity towards DNA make Hoechst dyes …
Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review
M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …
due to the special problems they have faced, such as their increasing diversity and …
A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise
The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …
medical imperative that in recent years motivates the talents of numerous investigators …
Developing novel coumarin-containing azoles antifungal agents by the scaffold merging strategy for treating azole-resistant candidiasis
Z Yan, Y Huang, D Zhao, Z Li, X Wang… - Journal of Medicinal …, 2023 - ACS Publications
The extensive use of antifungal drugs has resulted in severe drug resistance, making clinical
treatment of fungal infections more difficult. Biofilm inhibitors can overcome drug resistance …
treatment of fungal infections more difficult. Biofilm inhibitors can overcome drug resistance …
Antifungal activity and preliminary mechanism of pristimerin against Sclerotinia sclerotiorum
WB Zhao, ZM Zhao, Y Ma, AP Li, ZJ Zhang… - Industrial Crops and …, 2022 - Elsevier
Abstract Sclerotinia sclerotiorum (Lib.) de Bary is a crop-threatening fungus. Natural
products are ideal antimicrobial agents to combat pathogens. They are considered a …
products are ideal antimicrobial agents to combat pathogens. They are considered a …
Design, synthesis, and biological evaluation of dual-target COX-2/CYP51 inhibitors for the treatment of fungal infectious diseases
W Liu, Y Liu, H Fan, M Liu, J Han, Y An… - Journal of Medicinal …, 2022 - ACS Publications
The design of novel dual-target (COX-2/CYP51) inhibitors was proposed in the study, and
three series of compounds were constructed though the pathway of skeleton screening and …
three series of compounds were constructed though the pathway of skeleton screening and …
Distorted gold (I)–phosphine complexes as antifungal agents
Fungi cause serious nosocomial infections including candidiasis and aspergillosis, some of
which display reduced susceptibility to current antifungals. Inorganic compounds have been …
which display reduced susceptibility to current antifungals. Inorganic compounds have been …
Structure‐Activity Relationships for 5′′ Modifications of 4, 5‐Aminoglycoside Antibiotics
JCK Quirke, GC Sati, A Sonousi, M Gysin… - …, 2022 - Wiley Online Library
Abstract Modification at the 5''‐position of 4, 5‐disubstituted aminoglycoside antibiotics
(AGAs) to circumvent inactivation by aminoglycoside modifying enzymes (AMEs) is well …
(AGAs) to circumvent inactivation by aminoglycoside modifying enzymes (AMEs) is well …
Aminoglycoside antibiotic kanamycin functionalized tetraphenylethylene molecular probe for highly selective detection of bovine serum albumin protein
A novel tetraphenylethylene (TPE) functionalized aminoglycoside antibiotic kanamycin (TPE-
kana 1) has been successfully synthesized and characterized by means of modern …
kana 1) has been successfully synthesized and characterized by means of modern …