Transition metals-catalyzed amination of biomass feedstocks for sustainable construction of N-heterocycles

Q Yan, X Wu, H Jiang, H Wang, F Xu, H Li… - Coordination Chemistry …, 2024 - Elsevier
Transition metals, which are of diversity in their bonding orbitals, have a variety of significant
oxidation states and more complex chemical properties compared to the main group metals …

The use of hoechst dyes for DNA staining and beyond

J Bucevičius, G Lukinavičius, R Gerasimaitė - Chemosensors, 2018 - mdpi.com
Hoechst dyes are among the most popular fluorophores used to stain DNA in living and
fixed cells. Moreover, their high affinity and specificity towards DNA make Hoechst dyes …

Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review

M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …

A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise

KC Howard, EK Dennis, DS Watt… - Chemical Society …, 2020 - pubs.rsc.org
The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …

Developing novel coumarin-containing azoles antifungal agents by the scaffold merging strategy for treating azole-resistant candidiasis

Z Yan, Y Huang, D Zhao, Z Li, X Wang… - Journal of Medicinal …, 2023 - ACS Publications
The extensive use of antifungal drugs has resulted in severe drug resistance, making clinical
treatment of fungal infections more difficult. Biofilm inhibitors can overcome drug resistance …

Antifungal activity and preliminary mechanism of pristimerin against Sclerotinia sclerotiorum

WB Zhao, ZM Zhao, Y Ma, AP Li, ZJ Zhang… - Industrial Crops and …, 2022 - Elsevier
Abstract Sclerotinia sclerotiorum (Lib.) de Bary is a crop-threatening fungus. Natural
products are ideal antimicrobial agents to combat pathogens. They are considered a …

Design, synthesis, and biological evaluation of dual-target COX-2/CYP51 inhibitors for the treatment of fungal infectious diseases

W Liu, Y Liu, H Fan, M Liu, J Han, Y An… - Journal of Medicinal …, 2022 - ACS Publications
The design of novel dual-target (COX-2/CYP51) inhibitors was proposed in the study, and
three series of compounds were constructed though the pathway of skeleton screening and …

Distorted gold (I)–phosphine complexes as antifungal agents

EK Dennis, JH Kim, S Parkin, SG Awuah… - Journal of medicinal …, 2019 - ACS Publications
Fungi cause serious nosocomial infections including candidiasis and aspergillosis, some of
which display reduced susceptibility to current antifungals. Inorganic compounds have been …

Structure‐Activity Relationships for 5′′ Modifications of 4, 5‐Aminoglycoside Antibiotics

JCK Quirke, GC Sati, A Sonousi, M Gysin… - …, 2022 - Wiley Online Library
Abstract Modification at the 5''‐position of 4, 5‐disubstituted aminoglycoside antibiotics
(AGAs) to circumvent inactivation by aminoglycoside modifying enzymes (AMEs) is well …

Aminoglycoside antibiotic kanamycin functionalized tetraphenylethylene molecular probe for highly selective detection of bovine serum albumin protein

RW Jadhav, SM Wagalgave, BV Kumbhar… - Scientific Reports, 2022 - nature.com
A novel tetraphenylethylene (TPE) functionalized aminoglycoside antibiotic kanamycin (TPE-
kana 1) has been successfully synthesized and characterized by means of modern …