Recent advances in antimicrobial nano-drug delivery systems

TX Zong, AP Silveira, JAV Morais, MC Sampaio… - Nanomaterials, 2022 - mdpi.com
Infectious diseases are among the major health issues of the 21st century. The substantial
use of antibiotics over the years has contributed to the dissemination of multidrug resistant …

Design of olmesartan medoxomil-loaded nanosponges for hypertension and lung cancer treatments

BK Almutairy, A Alshetaili, AS Alali, MM Ahmed… - Polymers, 2021 - mdpi.com
Olmesartan medoxomil (OLM) is one of the prominent antihypertensive drug that suffers from
low aqueous solubility and dissolution rate leading to its low bioavailability. To improve the …

Nanomedicine for colon-targeted drug delivery: strategies focusing on inflammatory bowel disease and colon cancer

A Kumar, KK Vaiphei, N Singh… - …, 2024 - Taylor & Francis
The nanostructured drug-delivery systems for colon-targeted drug delivery are a promising
field of research for localized diseases particularly influencing the colonic region, in other …

Formulation of self-nanoemulsifying drug delivery system of cephalexin: physiochemical characterization and antibacterial evaluation

A Zafar, M Yasir, NK Alruwaili, SS Imam, OA Alsaidan… - Polymers, 2022 - mdpi.com
A cephalexin (CEP) self-nanoemulsifying drug delivery system (SNEDDS) was developed in
this study to improve the drug's oral administration. The CEP-SNEDDS was made utilizing …

Diosmin-loaded nanoemulsion-based gel formulation: Development, optimization, wound healing and anti-inflammatory studies

MK Anwer, MF Aldawsari, M Iqbal, BK Almutairy… - Gels, 2023 - mdpi.com
The wound-healing process is complex and prone to interruption or failure, which can result
in the development of chronic wounds that never heal. This can be overcome by seeking …

Development of apremilast nanoemulsion-loaded chitosan gels: In vitro evaluations and anti-inflammatory and wound healing studies on a rat model

MM Ahmed, MK Anwer, F Fatima, AS Alali, MA Kalam… - Gels, 2022 - mdpi.com
Apremilast (APL) has profound anti-inflammatory and wound healing activity, alongside
other dermal care. This study aims to develop APL-loaded NEs (ANE1-ANE5) using …

[HTML][HTML] Mannosylated preactivated hyaluronic acid-based nanostructures for bacterial infection treatment

R Arshad, MS Arshad, A Malik, M Alkholief… - International Journal of …, 2023 - Elsevier
Salmonella Typhi is an intracellular bacterium causing a variety of enteric diseases, being
typhoid fever the most common. Current modalities for treating S. typhi infection are …

A Quality by Design Approach for Developing SNEDDS Loaded with Vemurafenib for Enhanced Oral Bioavailability

C Jvus, N Kothuri, S Singh, S Verma, H Shafi… - AAPS …, 2024 - Springer
Vemurafenib (VMF) is a practically insoluble (< 0.1 μg/mL) and least bioavailable (1%) drug.
To enhance its oral bioavailability and solubility, we formulated a reliable self-nano …

Lactoferrin Reduces Surfactant Content in the Self-Emulsifying Drug Delivery System

H Khairnar, S Jain, B Chatterjee - ACS omega, 2024 - ACS Publications
Self-emulsifying drug delivery systems (SEDDSs) can effectively be employed to formulate
drugs with poor oral bioavailability due to low aqueous solubility and high first-pass …

[HTML][HTML] Isotretinoin self-nano-emulsifying drug delivery system: Preparation, optimization and antibacterial evaluation

R Alfaraj, S Hababah, EK Eltayb, FY Alqahtani… - Saudi Pharmaceutical …, 2024 - Elsevier
Purpose Isotretinoin (ITN) is a poorly water-soluble drug. The objective of this study was to
design a successful liquid self-nanoemulsifying drug delivery system (L-SNEDDS) for ITN to …