[HTML][HTML] Limitations of non-invasive tests for assessment of liver fibrosis

K Patel, G Sebastiani - JHEP Reports, 2020 - Elsevier
The diagnostic assessment of liver injury is an important step in the management of patients
with chronic liver disease (CLD). Although liver biopsy is the reference standard for the …

[HTML][HTML] Hepatic inflammation and progressive liver fibrosis in chronic liver disease

AJ Czaja - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Chronic liver inflammation drives hepatic fibrosis, and current immunosuppressive, anti-
inflammatory, and anti-viral therapies can weaken this driver. Hepatic fibrosis is reversed …

Evaluation of APRI and FIB-4 scoring systems for non-invasive assessment of hepatic fibrosis in chronic hepatitis B patients

WR Kim, T Berg, T Asselah, R Flisiak, S Fung… - Journal of …, 2016 - Elsevier
Background & Aims While the gold standard in the assessment of liver fibrosis remains liver
biopsy, non-invasive methods have been increasingly used for chronic hepatitis B (CHB) …

A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C

CT Wai, JK Greenson, RJ Fontana, JD Kalbfleisch… - Hepatology, 2003 - Elsevier
Information on the stage of liver fibrosis is essential in managing chronic hepatitis C (CHC)
patients. However, most models for predicting liver fibrosis are complicated and separate …

Sampling variability of liver fibrosis in chronic hepatitis C

P Bedossa, D Dargère, V Paradis - Hepatology, 2003 - journals.lww.com
Fibrosis is a common endpoint of clinical trials in chronic hepatitis C, and liver biopsy
remains the gold standard for fibrosis evaluation. However, variability in the distribution of …

Grading and staging systems for inflammation and fibrosis in chronic liver diseases

ZD Goodman - Journal of hepatology, 2007 - Elsevier
Liver biopsy is an important part of the evaluation of patients with a variety of liver diseases.
Besides establishing the diagnosis, the biopsy is often used to assess the severity of the …

Magnetic resonance elastography for the noninvasive staging of liver fibrosis

L Huwart, C Sempoux, E Vicaut, N Salameh, L Annet… - Gastroenterology, 2008 - Elsevier
Background & Aims: The purpose of our study was to prospectively compare the success
rate and diagnostic accuracy of magnetic resonance elastography, ultrasound elastography …

Nonalcoholic steatohepatitis: definition and pathology

EM Brunt - Seminars in liver disease, 2001 - thieme-connect.com
Nonalcoholic steatohepatitis (NASH) is a significant form of chronic liver disease in adults
and children. The natural history of NASH ranges from indolent to end-stage liver disease …

Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease

G Colloredo, M Guido, A Sonzogni, G Leandro - Journal of hepatology, 2003 - Elsevier
Background/Aims: In chronic viral hepatitis, liver biopsy is performed for assessing disease
activity and fibrosis. In this study, we evaluated the impact of the size of liver biopsy on the …

Evaluation of liver fibrosis: a concise review

NH Afdhal, D Nunes - Official journal of the American College of …, 2004 - journals.lww.com
The diagnosis of liver fibrosis has traditionally relied on liver biopsy. However, recent studies
have suggested that there can be up to a 33% error in the diagnosis of cirrhosis. In this …