Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

Mitochondrial metabolism must constantly adapt to stress conditions in order to maintain
bioenergetic levels related to cellular functions. This absence of proper adaptation can be …

Autophagy is a catabolic pathway by which cellular components are delivered to the
lysosome for degradation and recycling. Autophagy serves as a crucial intracellular quality …

Mitochondrial damage is implicated as a major contributing factor for a number of
noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and …

Taurine is a nonproteinogenic ß‐aminosulfonic acid. Important dietary sources of taurine are
fish and seafood. Taurine interacts with ion channels, stabilizes membranes, and regulates …

The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …

With global population aging, age-related diseases, especially sarcopenia, have attracted
much attention in recent years. Characterized by low muscle strength, low muscle quantity or …

Muscle differentiation is a crucial process controlling muscle development and homeostasis.
Mitochondrial reactive oxygen species (mtROS) rapidly increase and function as critical cell …

Exercise is among the most effective interventions for age-associated mobility decline and
metabolic dysregulation. Although long-term endurance exercise promotes insulin sensitivity …

Repetitive, calcium-mediated contractile activity renders cardiomyocytes critically dependent
on a sustained energy supply and adequate calcium buffering, both of which are provided …