Recent advances in aptamer discovery and applications

Y Zhang, BS Lai, M Juhas - Molecules, 2019 - mdpi.com
Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …

Aptamer-based biosensors for environmental monitoring

EM McConnell, J Nguyen, Y Li - Frontiers in chemistry, 2020 - frontiersin.org
Due to their relative synthetic and chemical simplicity compared to antibodies, aptamers
afford enhanced stability and functionality for the detection of environmental contaminants …

Nanocomposites (conducting polymer and nanoparticles) based electrochemical biosensor for the detection of environment pollutant: Its issues and challenges

H Kumar, N Kumari, R Sharma - Environmental Impact Assessment Review, 2020 - Elsevier
Currently, there is an urgent need to develop an electro-analytical technique that can detect
and monitor environmental pollutants in a sensitive, specific, and selective manner …

Cu-based metal–organic frameworks as a catalyst to construct a ratiometric electrochemical aptasensor for sensitive lipopolysaccharide detection

WJ Shen, Y Zhuo, YQ Chai, R Yuan - Analytical chemistry, 2015 - ACS Publications
In this work, we developed a sensitive and efficient ratiometric electrochemical method for
lipopolysaccharide (LPS) detection using Cu-based metal–organic frameworks (Cu-MOFs) …

Dually amplified electrochemical aptasensor for endotoxin detection via target-assisted electrochemically mediated ATRP

Q Hu, J Wan, Z Liang, S Li, W Feng, Y Liang… - Analytical …, 2023 - ACS Publications
As the entering of bacterial endotoxin into blood can cause various life-threatening
pathological conditions, the screening and detection of low-abundance endotoxin are of …

A novel labeled and label-free dual electrochemical detection of endotoxin based on aptamer-conjugated magnetic reduced graphene oxide-gold nanocomposite

M Zamani, M Pourmadadi, SAS Ebrahimi… - Journal of …, 2022 - Elsevier
Lipopolysaccharide (LPS) or endotoxin is an amphiphilic macromolecule found in the outer
membrane of gram-negative bacteria. Even low amounts of LPS could result in death …

Boronate affinity-amplified electrochemical aptasensing of lipopolysaccharide

Q Hu, W Feng, Y Liang, Z Liang, X Cao, S Li… - Analytical …, 2022 - ACS Publications
As lipopolysaccharide (LPS) is closely associated with sepsis and other life-threatening
conditions, the point-of-care (POC) detection of LPS is of significant importance to human …

Aptamer based electrochemical sensors for emerging environmental pollutants

A Hayat, JL Marty - Frontiers in chemistry, 2014 - frontiersin.org
Environmental contaminants monitoring is one of the key issues in understanding and
managing hazards to human health and ecosystems. In this context, aptamer based …

Nanomaterials for biosensing lipopolysaccharide

P Sondhi, MHU Maruf, KJ Stine - Biosensors, 2019 - mdpi.com
Lipopolysaccharides (LPS) are endotoxins, hazardous and toxic inflammatory stimulators
released from the outer membrane of Gram-negative bacteria, and are the major cause of …

Binding sugars: from natural lectins to synthetic receptors and engineered neolectins

J Arnaud, A Audfray, A Imberty - Chemical Society Reviews, 2013 - pubs.rsc.org
The large diversity and complexity of glycan structures together with their crucial role in
many biological or pathological processes require the development of new high-throughput …