Current perspectives on Stevens-Johnson syndrome and toxic epidermal necrolysis

M Lerch, C Mainetti, B Terziroli Beretta-Piccoli… - Clinical reviews in …, 2018 - Springer
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are considered a
delayed-type hypersensitivity reaction to drugs. They represent true medical emergencies …

[HTML][HTML] The diagnosis of limbal stem cell deficiency

Q Le, J Xu, SX Deng - The ocular surface, 2018 - Elsevier
Limbal stem cells (LSCs) maintain the normal homeostasis and wound healing of corneal
epithelium. Limbal stem cell deficiency (LSCD) is a pathologic condition that results from the …

SJS/TEN 2017: building multidisciplinary networks to drive science and translation

KD White, R Abe, M Ardern-Jones… - The Journal of Allergy …, 2018 - Elsevier
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening,
immunologically mediated, and usually drug-induced disease with a high burden to …

British Association of Dermatologists' guidelines for the management of Stevens–Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018

T McPherson, LS Exton, S Biswas… - British Journal of …, 2019 - academic.oup.com
British Association of Dermatologists' guidelines for the management of Stevens–Johnson
syndrome/toxic epidermal necrolysis in children and young people, 2018 | British Journal of …

[HTML][HTML] Pediatric SJS-TEN: Where are we now?

M Ramien, JL Goldman - F1000Research, 2020 - ncbi.nlm.nih.gov
Stevens–Johnson syndrome and toxic epidermal necrolysis are rare severe blistering skin
reactions triggered by medications or infections. Over the last 5 to 10 years, a number of …

Chronic ocular sequelae of Stevens-Johnson syndrome in children: long-term impact of appropriate therapy on natural history of disease

S Basu, SS Shanbhag, A Gokani, R Kedar… - American Journal of …, 2018 - Elsevier
Purpose To describe the long-term ocular and visual morbidity in children with chronic
sequelae of Stevens-Johnson syndrome (SJS) and visual outcomes of various management …

Lid margin keratinization in Stevens-Johnson syndrome: Review of pathophysiology and histopathology

S Singh, S Jakati, SS Shanbhag, AM Elhusseiny… - The Ocular Surface, 2021 - Elsevier
Lid margin keratinization (LMK) is a chronic ocular sequela of Stevens-Johnson syndrome
(SJS), which causes lid wiper epitheliopathy and progressive ocular surface damage. The …

Long-term PM2. 5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models

S Hao, Z Chen, Y Gu, L Chen, F Sheng, Y Xu… - Particle and Fibre …, 2023 - Springer
Background Limbal stem/progenitor cells (LSPCs) play a crucial role in maintaining corneal
health by regulating epithelial homeostasis. Although PM2. 5 is associated with the …

Ocular manifestations of Stevens–Johnson syndrome and their management

HN Saeed, J Chodosh - Current opinion in ophthalmology, 2016 - journals.lww.com
The literature overwhelmingly describes acute intervention for ocular involvement in
SJS/TEN as improving long-term outcomes. All patients admitted for SJS/TEN or suspicion of …

[HTML][HTML] Topical Betamethasone Treatment of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis with Ocular Involvement in the Acute Phase

K Matsumoto, M Ueta, T Inatomi, H Fukuoka… - American Journal of …, 2023 - Elsevier
PURPOSE To clarify the importance of administering topical steroids for the treatment of
Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with ocular involvement …