Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

[HTML][HTML] Pseudomonas aeruginosa: an antibiotic resilient pathogen with environmental origin

P Laborda, F Sanz-García, S Hernando-Amado… - Current Opinion in …, 2021 - Elsevier
Highlights•P. aeruginosa is opportunistic pathogen with an environmental origin.•P.
aeruginosa presents low susceptibility to currently used antibiotics.•P. aeruginosa displays a …

Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape

DM Muloi, BA Wee, DMH McClean, MJ Ward… - Nature …, 2022 - nature.com
Quantitative evidence for the risk of zoonoses and the spread of antimicrobial resistance
remains lacking. Here, as part of the UrbanZoo project, we sampled Escherichia coli from …

Next-generation microbiology: from comparative genomics to gene function

CM Kobras, AK Fenton, SK Sheppard - Genome Biology, 2021 - Springer
Microbiology is at a turning point in its 120-year history. Widespread next-generation
sequencing has revealed genetic complexity among bacteria that could hardly have been …

The Avian Pathogenic Escherichia coli (APEC) pathotype is comprised of multiple distinct, independent genotypes

JW Mehat, AHM van Vliet, RM La Ragione - Avian Pathology, 2021 - Taylor & Francis
ABSTRACT Avian Pathogenic E. coli (APEC) is the causative agent of avian colibacillosis,
resulting in economic losses to the poultry industry through morbidity, mortality and carcass …

Genome wide association study of Escherichia coli bloodstream infection isolates identifies genetic determinants for the portal of entry but not fatal outcome

E Denamur, B Condamine, M Esposito-Farese… - PLoS …, 2022 - journals.plos.org
Escherichia coli is an important cause of bloodstream infections (BSI), which is of concern
given its high mortality and increasing worldwide prevalence. Finding bacterial genetic …

[HTML][HTML] Genomic characteristics, virulence, and antimicrobial resistance in avian pathogenic Escherichia coli MTR_BAU02 strain isolated from layer farm in …

S Ievy, MN Hoque, MS Islam, MA Sobur… - Journal of Global …, 2022 - Elsevier
Background Colibacillosis, caused by avian pathogenic Escherichia coli (APEC), is one of
the most significant infectious diseases affecting poultry worldwide. Objectives This study …

Functions predict horizontal gene transfer and the emergence of antibiotic resistance

H Zhou, JF Beltrán, IL Brito - Science advances, 2021 - science.org
Phylogenetic distance, shared ecology, and genomic constraints are often cited as key
drivers governing horizontal gene transfer (HGT), although their relative contributions are …

Combined comparative genomics and clinical modeling reveals plasmid-encoded genes are independently associated with Klebsiella infection

J Vornhagen, EK Roberts, L Unverdorben… - Nature …, 2022 - nature.com
Members of the Klebsiella pneumoniae species complex frequently colonize the gut and
colonization is associated with subsequent infection. To identify genes associated with …

Refining the definition of the avian pathogenic Escherichia coli (APEC) pathotype through inclusion of high-risk clonal groups

TJ Johnson, EA Miller, C Flores-Figueroa… - Poultry science, 2022 - Elsevier
Colibacillosis in poultry is a unique disease manifestation of Escherichia coli in the animal
world, as one of the primary routes of entry is via the respiratory tract of birds. Because of …