[HTML][HTML] Hypothesis: artifacts, including spurious chimeric RNAs with a short homologous sequence, caused by consecutive reverse transcriptions and endogenous …
Z Peng, C Yuan, L Zellmer, S Liu, N Xu… - Journal of Cancer, 2015 - ncbi.nlm.nih.gov
Recent RNA-sequencing technology and associated bioinformatics have led to identification
of tens of thousands of putative human chimeric RNAs, ie RNAs containing sequences from …
of tens of thousands of putative human chimeric RNAs, ie RNAs containing sequences from …
Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans
S Chatterjee, U Tatu - PLoS neglected tropical diseases, 2017 - journals.plos.org
Background Thermotolerance is an essential attribute for pathogenesis of Cryptococcus as
exemplified by the fact that only two species in the genus, which can grow at 37° C, are …
exemplified by the fact that only two species in the genus, which can grow at 37° C, are …
[HTML][HTML] Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics
Cyst formation in the parasitic protist Giardia duodenalis is critical to its transmission.
Existing proteomic data quantifies only 17% of coding genes transcribed during encystation …
Existing proteomic data quantifies only 17% of coding genes transcribed during encystation …
Heat Shock Protein 90 regulates encystation in Entamoeba
Enteric protozoan Entamoeba histolytica is a major cause of debilitating diarrheal infection
worldwide with high morbidity and mortality. Even though the clinical burden of this parasite …
worldwide with high morbidity and mortality. Even though the clinical burden of this parasite …
In vivo Validation of Hsp90 Trans-splicing in Giardia lamblia: Highlighting the Role of Cis-elements
S Tushir, P Jhanwar, M Benda, V Horáčková… - Journal of Molecular …, 2024 - Elsevier
Giardia lamblia causes giardiasis, one of the most common human infectious diseases
globally. Previous studies from our lab have shown that hsp90 gene of Giardia is split into …
globally. Previous studies from our lab have shown that hsp90 gene of Giardia is split into …
A secreted Heat shock protein 90 of Trichomonas vaginalis
Trichomonas vaginalis is a causative agent of Trichomoniasis, a leading non-viral sexually
transmitted disease worldwide. In the current study, we show Heat shock protein 90 is …
transmitted disease worldwide. In the current study, we show Heat shock protein 90 is …
Giardia lamblia Hsp90 pre‐mRNAs undergo self‐splicing to generate mature RNA in an in vitro trans‐splicing reaction
We have previously shown that the Heat Shock Protein 90 (Hsp90) gene in G. lamblia is
expressed from two ORF s localized 777 kb apart. The pre‐mRNA s transcribed from these …
expressed from two ORF s localized 777 kb apart. The pre‐mRNA s transcribed from these …
Differential antibody responses to Giardia lamblia strain variants expressing dissimilar levels of an immunogenic protein
T Garzon, L Valencia, V Dominguez… - Parasite …, 2020 - Wiley Online Library
Aims Giardia lamblia is a protozoan parasite that causes giardiasis, one of the most common
worldwide gastrointestinal diseases. For rational development of a Giardia vaccine …
worldwide gastrointestinal diseases. For rational development of a Giardia vaccine …
Protists: Eukaryotic single-celled organisms and the functioning of their organelles.
N Yarlett, EL Jarroll, M Morada… - Advances in Microbial …, 2024 - europepmc.org
Organelles are membrane bound structures that compartmentalize biochemical and
molecular functions. With improved molecular, biochemical and microscopy tools the …
molecular functions. With improved molecular, biochemical and microscopy tools the …
Network of Entamoeba histolytica HSP18.5 dimers formed by two overlapping [IV]‐X‐[IV] motifs
D Kurre, K Suguna - Proteins: Structure, Function, and …, 2021 - Wiley Online Library
Small heat shock proteins (sHSPs) are ATP‐independent molecular chaperones with low
molecular weight that prevent the aggregation of proteins during stress conditions and …
molecular weight that prevent the aggregation of proteins during stress conditions and …