Cardiovascular involvement in patients affected by acromegaly: an appraisal
Cardiovascular complications are frequent in acromegalic patients. Several studies reported
increased prevalence of traditional cardiovascular risk factors and early development of …
increased prevalence of traditional cardiovascular risk factors and early development of …
[HTML][HTML] The effect of endocrine disorders on lipids and lipoproteins
KR Feingold, EA Brinton, C Grunfeld - 2017 - europepmc.org
Endocrine disorders and the administration of various hormones can alter lipid metabolism
and plasma lipid levels, which may increase or decrease the risk of atherosclerotic …
and plasma lipid levels, which may increase or decrease the risk of atherosclerotic …
The impact of adipose tissue on insulin resistance in acromegaly
NC Olarescu, J Bollerslev - Trends in Endocrinology & Metabolism, 2016 - cell.com
Adipose tissue (AT) is recognized as key contributor to the systemic insulin resistance and
overt diabetes seen in metabolic syndrome. Acromegaly is a disease characterized by …
overt diabetes seen in metabolic syndrome. Acromegaly is a disease characterized by …
Acromegaly, inflammation and cardiovascular disease: a review
Acromegaly is characterized by Growth Hormone (GH) and Insulin-like Growth Factor 1 (IGF-
1) excess. Uncontrolled acromegaly is associated with a strongly increased risk of …
1) excess. Uncontrolled acromegaly is associated with a strongly increased risk of …
IGF-1 levels across the spectrum of normal to elevated in acromegaly: relationship to insulin sensitivity, markers of cardiovascular risk and body composition
Purpose Activity of acromegaly is gauged by levels of GH and IGF-1 and epidemiological
studies demonstrate that their normalization reduces acromegaly's excess mortality rate …
studies demonstrate that their normalization reduces acromegaly's excess mortality rate …
Effects of endocrine disorders on lipids and lipoproteins
CB Newman - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Endocrine diseases may be associated with dyslipidaemia and may increase atherosclerotic
cardiovascular disease (ASCVD) risk. This chapter describes changes in lipids and …
cardiovascular disease (ASCVD) risk. This chapter describes changes in lipids and …
The acromegaly lipodystrophy
PU Freda - Frontiers in endocrinology, 2022 - frontiersin.org
Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth,
metabolism, and body composition, but in acromegaly, excesses of these hormones …
metabolism, and body composition, but in acromegaly, excesses of these hormones …
The endothelium in acromegaly
P Maffei, F Dassie, A Wennberg, M Parolin… - Frontiers in …, 2019 - frontiersin.org
Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known
deleterious effects on the cardiovascular system, especially after long-term exposition …
deleterious effects on the cardiovascular system, especially after long-term exposition …
HOMA-IR in acromegaly: a systematic review and meta-analysis
B Biagetti, A Aulinas, A Casteras, S Perez-Hoyos… - Pituitary, 2021 - Springer
Purpose This review is aimed at examining whether the Homeostatic Model Assessment of
Insulin Resistance (HOMA-IR) is higher in Caucasian, adult, treatment-naïve patients with …
Insulin Resistance (HOMA-IR) is higher in Caucasian, adult, treatment-naïve patients with …
Prospective study of surgical treatment of acromegaly: effects on ghrelin, weight, adiposity, and markers of CV risk
C Reyes-Vidal, JC Fernandez, JN Bruce… - The Journal of …, 2014 - academic.oup.com
Context: Although epidemiological studies have found that GH and IGF-1 normalization
reduce the excess mortality of active acromegaly to expected rates, cross-sectional data …
reduce the excess mortality of active acromegaly to expected rates, cross-sectional data …