The IL-2 receptor complex: its structure, function, and target genes.
Y Minami, T Kono, T Miyazaki… - Annual review of …, 1993 - europepmc.org
Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor
following T lymphocyte activation. The receptor for IL-2 consists of at least three distinct …
following T lymphocyte activation. The receptor for IL-2 consists of at least three distinct …
The hematopoietin receptor superfamily
D Cosman - Cytokine, 1993 - Elsevier
The receptors for a number of cytokines show amino acid sequence homologies in their
extracellular domains that define a new family of molecules, the hematopoietin receptors …
extracellular domains that define a new family of molecules, the hematopoietin receptors …
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
J Kunz, R Henriquez, U Schneider, M Deuter-Reinhard… - Cell, 1993 - cell.com
The yeast TOR2 gene encodes an essential 282 kd phosphatidylinositol (PI) 3-kinase
homolog. TOR2 is related to the catalytic subunit of bovine PI 3-kinase and to yeast VPS34 …
homolog. TOR2 is related to the catalytic subunit of bovine PI 3-kinase and to yeast VPS34 …
Signal transduction in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: Activation of protein tyrosine kinases and …
SD Tachado, P Gerold, R Schwarz… - Proceedings of the …, 1997 - National Acad Sciences
The perturbation of various glycosylphosphatidylinositol (GPI)-anchored surface proteins
imparts profound regulatory signals to macrophages, lymphocytes and other cell types. The …
imparts profound regulatory signals to macrophages, lymphocytes and other cell types. The …
Isolation of interleukin 2-induced immediate-early genes.
C Beadling, KW Johnson… - Proceedings of the …, 1993 - National Acad Sciences
Clonal expansion of antigen-reactive T lymphocytes is driven by the lymphokine interleukin
2 (IL-2). To further elucidate the mechanisms of IL-2 action, we have utilized a differential …
2 (IL-2). To further elucidate the mechanisms of IL-2 action, we have utilized a differential …
The common γ-chain for multiple cytokine receptors
K Sugamura, H Asao, M Kondo, N Tanaka, N Ishii… - Advances in …, 1995 - Elsevier
Publisher Summary The chapter focuses on the common γ chain for multiple cytokine
receptors. The signal transducers are composed of both common and specific molecules for …
receptors. The signal transducers are composed of both common and specific molecules for …
Phosphatidic Acid Generation through Interleukin 2 (IL-2)-induced α-Diacylglycerol Kinase Activation Is an Essential Step in IL-2-mediated Lymphocyte Proliferation …
I Flores, T Casaseca, C Martinez-A, H Kanoh… - Journal of Biological …, 1996 - ASBMB
Proliferation of T lymphocytes is triggered by the interaction of interleukin 2 (IL-2) with its
high affinity specific receptor that is expressed on the cell surface following T lymphocyte …
high affinity specific receptor that is expressed on the cell surface following T lymphocyte …
Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine …
Background The dominant, cell surface lipophosphoglycan (LPG) of Leishmania is a
multifunctional molecule involved in the interaction with vertebrate and invertebrate hosts …
multifunctional molecule involved in the interaction with vertebrate and invertebrate hosts …
Interleukin-2
KA Smith - Current opinion in immunology, 1992 - Elsevier
In the past year there have been significant advances in understanding the role of
interleukin-2. Its role in the activation of T cells by antigen-presenting cells, the structure …
interleukin-2. Its role in the activation of T cells by antigen-presenting cells, the structure …
Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway
Y Minami, Y Nakagawa, A Kawahara, T Miyazaki… - Immunity, 1995 - cell.com
Summary The IL-2 receptor (IL-2R) consists of three subunits, the IL-2Ra, IL-PRp, and IL-
2Ry chains. The IL-linduced proliferative signals emanate from the cytoplasmic domains of …
2Ry chains. The IL-linduced proliferative signals emanate from the cytoplasmic domains of …