Arterial calcification in chronic kidney disease: key roles for calcium and phosphate
Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …
The role of the calcium-sensing receptor in human disease
BK Ward, AL Magno, JP Walsh, T Ratajczak - Clinical biochemistry, 2012 - Elsevier
Following the discovery of the calcium-sensing receptor (CaSR) in 1993, its pivotal role in
disorders of calcium homeostasis such as Familial Hypocalciuric Hypercalcemia (FHH) was …
disorders of calcium homeostasis such as Familial Hypocalciuric Hypercalcemia (FHH) was …
Integration Of Extracellular And Intracellular Signals Via The Calcium Sensing Receptor (CASR)
C Zhang - 2014 - scholarworks.gsu.edu
Abstract The Ca 2+-sensing receptor (CaSR) regulates the calcium homeostasis in the
human body via sensing fluctuations in the extracellular Ca 2+ concentration. Naturally …
human body via sensing fluctuations in the extracellular Ca 2+ concentration. Naturally …
Expression of adrenomedullin in human epicardial adipose tissue: role of coronary status
Epicardial white adipose tissue (eWAT) is in close contact with coronary vessels and
therefore could alter coronary homeostasis. Adrenomedullin (AM) is a potent vasodilatator …
therefore could alter coronary homeostasis. Adrenomedullin (AM) is a potent vasodilatator …
Calcium-sensing receptor (CaSR), its impact on inflammation and the consequences on cardiovascular health
SS Sundararaman, EPC van der Vorst - International journal of molecular …, 2021 - mdpi.com
The calcium Sensing Receptor (CaSR) is a cell surface receptor belonging to the family of G-
protein coupled receptors. CaSR is mainly expressed by parathyroid glands, kidneys, bone …
protein coupled receptors. CaSR is mainly expressed by parathyroid glands, kidneys, bone …
Agonist-driven maturation and plasma membrane insertion of calcium-sensing receptors dynamically control signal amplitude
MP Grant, A Stepanchick, A Cavanaugh… - Science …, 2011 - science.org
Calcium-sensing receptors (CaSRs) regulate systemic calcium homeostasis in the
parathyroid gland, kidney, intestine, and bone and translate fluctuations in serum calcium …
parathyroid gland, kidney, intestine, and bone and translate fluctuations in serum calcium …
Extracellular calcium modulates in vitro bone marrow-derived Flk-1+ CD34+ progenitor cell chemotaxis and differentiation through a calcium-sensing receptor
Angiogenesis is a complex process regulated by many cell types and a large variety of
biochemical signals such as growth factors, transcription factors, oxygen and nutrient …
biochemical signals such as growth factors, transcription factors, oxygen and nutrient …
Molecular basis of the extracellular ligands mediated signaling by the calcium sensing receptor
Ca2+-sensing receptors (CaSRs) play a central role in regulating extracellular calcium
concentration ([Ca2+] o) homeostasis and many (patho) physiological processes in multiple …
concentration ([Ca2+] o) homeostasis and many (patho) physiological processes in multiple …
The calcium sensing receptor: from calcium sensing to signaling
Abstract The Ca 2+-sensing receptor (the CaSR), a G-protein-coupled receptor, regulates
Ca 2+ homeostasis in the body by monitoring extracellular levels of Ca 2+([Ca 2+] o) and …
Ca 2+ homeostasis in the body by monitoring extracellular levels of Ca 2+([Ca 2+] o) and …
[HTML][HTML] A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia
N Koleganova, G Piecha, E Ritz, CP Schmitt… - Kidney international, 2009 - Elsevier
Renal insufficiency increases cardiovascular risk, accelerates atherogenesis, and causes
vascular wall remodeling. Here we evaluated the effect of the calcimimetic R-568 and non …
vascular wall remodeling. Here we evaluated the effect of the calcimimetic R-568 and non …