Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …

Following the discovery of the calcium-sensing receptor (CaSR) in 1993, its pivotal role in
disorders of calcium homeostasis such as Familial Hypocalciuric Hypercalcemia (FHH) was …

Abstract The Ca 2+-sensing receptor (CaSR) regulates the calcium homeostasis in the
human body via sensing fluctuations in the extracellular Ca 2+ concentration. Naturally …

Epicardial white adipose tissue (eWAT) is in close contact with coronary vessels and
therefore could alter coronary homeostasis. Adrenomedullin (AM) is a potent vasodilatator …

The calcium Sensing Receptor (CaSR) is a cell surface receptor belonging to the family of G-
protein coupled receptors. CaSR is mainly expressed by parathyroid glands, kidneys, bone …

Calcium-sensing receptors (CaSRs) regulate systemic calcium homeostasis in the
parathyroid gland, kidney, intestine, and bone and translate fluctuations in serum calcium …

Angiogenesis is a complex process regulated by many cell types and a large variety of
biochemical signals such as growth factors, transcription factors, oxygen and nutrient …

Ca2+-sensing receptors (CaSRs) play a central role in regulating extracellular calcium
concentration ([Ca2+] o) homeostasis and many (patho) physiological processes in multiple …

Abstract The Ca 2+-sensing receptor (the CaSR), a G-protein-coupled receptor, regulates
Ca 2+ homeostasis in the body by monitoring extracellular levels of Ca 2+([Ca 2+] o) and …

Renal insufficiency increases cardiovascular risk, accelerates atherogenesis, and causes
vascular wall remodeling. Here we evaluated the effect of the calcimimetic R-568 and non …