Innate immune cells, particularly macrophages and epithelial cells, play a key role in
multiple layers of immune responses. Alarmins and pro-inflammatory cytokines from the IL …

A growing body of evidence supports a role for intrauterine infection in preterm labor and
preterm premature rupture of membranes (PROM). This article reviews the definition …

In order to assess the potential of procalcitonin measurement in the management of
neonatal sepsis, daily variations in serum procalcitonin (measured by an …

The role of infection in the pathogenesis of preterm labor and delivery, and the specific
mechanisms through which this association is demonstrated are presented. Cellular and …

Background Neonatal infections annually claim lives of 1.4 million neonates worldwide. Until
now, there is no ideal diagnostic test for detecting sepsis and thus management of possible …

Malaria in pregnancy predisposes to maternal anemia and low birth weight (LBW). We
examined the possible roles of the cytokines tumor necrosis factor alpha (TNF-α) and …

3. Assess the methodology of published studies that have reported on the role of cytokines
in the diagnosis of newborn sepsis. 4. Describe the accuracy of reported studies. 5. Evaluate …

Objective: Neonates born to mothers with clinical chorioamnionitis at term are at an
increased risk of infection. Acute subchorionitis, chorioamnionitis, and funisitis are …

Background Genetic variation in the innate immune system of the host may play a role in
determining the risk of developing infection, as well as outcome from infection. Methods …

Sex influences the severity and evolution of various inflammatory conditions. Although many
studies have demonstrated the role of sex hormones in immune response modulation …