After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …

Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency
as well as zinc excess result in severe disturbances in immune cell numbers and activities …

Zinc is an essential element and serves as a structural or catalytic component in many
proteins. Two families of transporters are involved in maintaining cellular zinc homeostasis …

Background Breast cancer (BC) is the most prevalent cancer and the main cause of cancer
deaths among females around the world. For early diagnosis of BC, there would be an …

The interconnection of microRNAs (miRNAs) and metal ions governs multiple biological
processes in disease development and progression. However, developing multiplexed tools …

MicroRNAs can exhibit opposite functions in different tumors. MiR-31 is a representative
example as it can not only enhance tumor development and progression in pancreatic …

Nutrimiromics studies the influence of the diet on the modification of gene expression due to
epigenetic processes related to microRNAs (miRNAs), which may affect the risk for the …

Despite substantial progress in understanding the cancer signaling network, effective
therapies remain scarce due to insufficient disruption of oncogenic pathways, drug …

The vast knowledge of the physiologic functions of zinc in at least 3000 proteins and the
recent recognition of fundamental regulatory functions of zinc (II) ions released from cells or …

The oncogenic miR-21 has been widely recognized to promote the development and
progression of various types of malignant tumors, but not cervical cancers. The aim of this …