[HTML][HTML] Pericytes in the renal vasculature: roles in health and disease

I Shaw, S Rider, J Mullins, J Hughes… - Nature Reviews …, 2018 - nature.com
In the dense circulatory system of the kidney, as in all vascularized tissues, pericytes enwrap
capillaries and microvessels to regulate angiogenesis, stabilize microvascular networks and …

11Beta-hydroxylase deficiency and other syndromes of mineralocorticoid excess as a rare cause of endocrine hypertension

E Melcescu, J Phillips, G Moll… - Hormone and …, 2012 - thieme-connect.com
Hypertension represents a major public and global health problem, most of which likely can
be improved by lifestyle changes including changing dietary habits with less consumption of …

Approach to the patient: reninoma

AG Hayes, M Stowasser… - The Journal of …, 2024 - academic.oup.com
A reninoma is a functional tumor of afferent arteriolar juxtaglomerular cells that secretes the
enzyme renin, leading to hyperactivation of the renin-angiotensin-aldosterone system …

Reninoma: an uncommon cause of renin-mediated hypertension

P Trnka, L Orellana, M Walsh, L Pool, P Borzi - Frontiers in pediatrics, 2014 - frontiersin.org
Reninoma (juxtaglomerular cell tumor) is a rare cause of renin-mediated hypertension.
Reninomas are usually diagnosed in adolescents and young adults with occasional reports …

Usefulness of magnetic resonance imaging in the diagnosis of juxtaglomerular cell tumors: a report of 10 cases and review of the literature

AL Faucon, C Bourillon, C Grataloup, S Baron… - American Journal of …, 2019 - Elsevier
Juxtaglomerular cell tumors (JCTs), a rare but potentially curable cause of hypertension, are
difficult to diagnose because they may be missed or misidentified as a cyst by computed …

Juxtaglomerular cell phenotypic plasticity

AG Martini, AHJ Danser - High Blood Pressure & Cardiovascular …, 2017 - Springer
Renin is the first and rate-limiting step of the renin-angiotensin system. The exclusive source
of renin in the circulation are the juxtaglomerular cells of the kidney, which line the afferent …

Juxtaglomerular cell tumor: reviewing a cryptic cause of surgically correctable hypertension

R Inam, J Gandhi, G Joshi, NL Smith, SA Khan - Current Urology, 2019 - journals.lww.com
Juxtaglomerular cell tumor (JGCT), or reninoma, is a typically benign neoplasm generally
affecting adolescents and young adults due to modified smooth muscle cells from the …

Reninoma: the importance of renal vein renin ratios for lateralisation and diagnosis

M Wolley, RD Gordon, M Stowasser - American Journal of Nephrology, 2014 - karger.com
Abstract Background/Aim: Reninomas are rare juxtaglomerular tumours which can cause
severe hypertension and hypokalaemia. Diagnosis can be problematic and these tumours …

A kidney tumor in an adolescent with severe hypertension and hypokalemia: an uncommon case–case report and review of the literature on reninoma

F Gottardo, M Cesari, A Morra, M Gardiman… - Urologia …, 2010 - karger.com
This report presents a case of a 16-year-old hypertensive boy who presented to our clinic.
Laboratory findings showed severe hypokalemia and markedly increased plasma renin …

Molecular Characterization of Juxtaglomerular Cell Tumors: Evidence of Alterations in MAPK–RAS Pathway

J Lobo, S Canete-Portillo, MDCR Pena, JK McKenney… - Modern Pathology, 2024 - Elsevier
Juxtaglomerular cell tumor (JGCT) is a rare neoplasm, part of the family of mesenchymal
tumors of the kidney. Although the pathophysiological and clinical correlates of JGCT are …