Background Acid-sensing ion channels (ASICs) are a group of amiloride-sensitive ligand-
gated ion channels belonging to the family of degenerin/epithelial sodium channels. ASICs …

Basic science research in tissue engineering and regenerative medicine aims to investigate
and understand the deposition, growth, and remodeling of tissues by drawing together …

Although the transient receptor potential vanilloid 4 (TRPV4) has been implicated in the
process of osmomechanical transduction, it appears to make little contribution to the normal …

Acidsensing ion channels (ASIC s) are voltageinsensitive cation channels responding to
extracellular acidification. ASIC proteins have two transmembrane domains and a large …

Mechanotransduction is the process by which physical forces are sensed and converted into
biochemical signals that then result in cellular responses. The discovery and development of …

Benign and malignant fibroproliferative disorders (FPDs) include idiopathic pulmonary
fibrosis, hepatic cirrhosis, myelofibrosis, systemic sclerosis, Dupuytren's contracture …

In the mammalian somatosensory system, mechanosensitive neurons mediate the senses of
touch and pain. Among sensory modalities, mechanosensation has been the most elusive …

The gating of ion channels by mechanical force underlies the sense of touch and pain. The
mode of gating of mechanosensitive ion channels in vertebrate touch receptors is unknown …

[Purpose] Instrument Assisted Soft Tissue Mobilization (IASTM) is a form of manual therapy.
Despite its growing popularity and an increasing number of patients receiving IASTM each …

Background: Integrin β1, as a member of the adhesion molecule family, is widely distributed
in many kinds of cells and participates in multiple biological functions of the nervous system …