Applications and challenges of ultra-small particle size nanoparticles in tumor therapy

J Xu, M Song, Z Fang, L Zheng, X Huang… - Journal of Controlled …, 2023 - Elsevier
With the development of nanotechnology, nanomedicines are widely used in tumor therapy.
However, biological barriers in the delivery of nanoparticles still limit their application in …

Entry of nanoparticles into cells: The importance of nanoparticle properties

J Zhao, MH Stenzel - Polymer Chemistry, 2018 - pubs.rsc.org
Knowledge of the interactions between nanoparticles (NPs) and cell membranes is of great
importance for the design of safe and efficient nanomedicines. Extensive studies aimed at …

New generation cadmium-free quantum dots for biophotonics and nanomedicine

G Xu, S Zeng, B Zhang, MT Swihart, KT Yong… - Chemical …, 2016 - ACS Publications
This review summarizes recent progress in the design and applications of cadmium-free
quantum dots (Cd-free QDs), with an emphasis on their role in biophotonics and …

Effect of nanoparticle composition, size, shape, and stiffness on penetration across the blood–brain barrier

TD Brown, N Habibi, D Wu, J Lahann… - … Science & Engineering, 2020 - ACS Publications
The delivery of therapeutics to the brain in an efficient, noninvasive manner continues to be
a major unmet need in the field of drug delivery. One significant impediment to brain delivery …

The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review

Y Cao, Y Gong, L Liu, Y Zhou, X Fang… - Journal of Applied …, 2017 - Wiley Online Library
With the rapid development of nanotechnologies, nanoparticles (NPs) are increasingly
produced and used in many commercial products, which could lead to the contact of human …

Polystyrene nanoplastics exposure caused defective neural tube morphogenesis through caveolae-mediated endocytosis and faulty apoptosis

J Nie, Y Shen, M Roshdy, X Cheng, G Wang… - Nanotoxicology, 2021 - Taylor & Francis
Growing evidence demonstrated that bioaccumulation of polystyrene nanoplastics (PS-NPs)
in various organisms including human beings caused destructive effects on health …

Advances in porous silicon–based nanomaterials for diagnostic and therapeutic applications

T Tieu, M Alba, R Elnathan… - Advanced …, 2019 - Wiley Online Library
This review provides a perspective on porous silicon (pSi)–based nanomaterials including
nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy …

Human mesenchymal stem cells differentiate into an osteogenic lineage in presence of strontium containing bioactive glass nanoparticles

P Naruphontjirakul, O Tsigkou, S Li, AE Porter… - Acta biomaterialia, 2019 - Elsevier
While bioactive glass and ions released during its dissolution are known to stimulate
osteoblast cells, the effect bioactive glass has on human stem cells is not clear. Here, we …

Toxicity assessment in the nanoparticle era

V De Matteis, R Rinaldi - Cellular and molecular toxicology of …, 2018 - Springer
The wide use of engineered nanomaterials in many fields, ranging from biomedical,
agriculture, environment, cosmetic, urged the scientific community to understand the …

Inhalable lactoferrin–chondroitin nanocomposites for combined delivery of doxorubicin and ellagic acid to lung carcinoma

MM Abd Elwakil, MT Mabrouk, MW Helmy… - …, 2018 - Taylor & Francis
Aim: The use of inhalable nanomedicines can overcome the Enhanced permeation and
retention effect (EPR)-associated drawbacks in lung cancer therapy via systemic …